Objective To explore the effect of continuous cold compress and intermittent cold compress on the extraction of impacted mandibular wisdom teeth.Methods From November 2018 to July 2019, 96 patients with impacted mandibular wisdom teeth were selected and divided into continuous group and intermittent group, each had 48 cases.All patients were kept in hospital for 24 h after tooth extraction and received routine nursing.On this basis, the continuous group accepted 24 h continuous cold compress, and the intermittent group accepted 24 h intermittent nursing.The degree of facial swelling, the degree of pain and the local skin temperature were measured at 6, 12 and 24 hours after operation.Results There was no statistically significant difference in the degree of facial swelling between the two groups at 6 hours after surgery (P>0.05);the degree of facial swelling at the 12 and 24 hours after surgery in the continuous group were lower than those in the intermittent group (P<0.05).The pain levels in the continuous group were lower than those in the intermittent group at 6, 12, and 24 hours after operation, and the differences were statistically significant (P<0.05).The skin temperature of the continuous group were lower than those of the intermittent group at 6,12, and 24 hours after operation, and the differences were statistically significant (P<0.05).Conclusion Compared with intermittent cold compress, continuous cold compress can improve the facial skin temperature and swelling degree of patients with impacted wisdom teeth after extraction, and reduce the pain degree of patients, which is worthy of clinical application.