抗菌药物管理对Ⅰ类切口手术围术期抗菌药物使用合理性的影响

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Abstract Objective To explore the effect of antimicrobial stewardship on the rationality of antimicrobial use in perioperative period of type Ⅰincision surgery.Methods From April 2018 to November 2019, 300 inpatients who underwent type Ⅰincision surgery in our hospital were selected as the research objects.January 2019 was taken as the official practice point of antimicrobial stewardship.From April to December 2018, the 148 patients admitted to our hospital were considered as before management, and the 152 patients from January to November 2019 were treated as after management.The proportion of antimicrobial use before and after antimicrobial stewardship and the prophylactive use of antibacterial drugs in patients with type I incision surgery were compared.Results After the implementation of management, the use rate of antimicrobial drugs for type I incision surgery decreased from 79.73% (118/148) before management to 21.71% (33/152), the difference was statistically significant (P＜0.05).The type of preventive use of antibacterial drugs in the perioperative period before antibacterial stewardship was mainly the first and third generation cephalosporins, and there was a phenomenon of drug combination.After management of antibacterial stewardship, the first and second generation cephalosporins took the majority without joint use, and the use rate of the first, second and third generation cephalosporins after management, compared with before management, the differences were statistically significant (P＜0.05).For other antibacterial drugs, there was no significant difference in use rate before and after management (P＞0.05).After management of antibacterial stewardship, the clinical selection of drug varieties, the duration of drug administration, and the reasonable rate of drug administration were higher than those before the management, and the rate of medication without indication, improper usage and dosage, and inappropriate choice of solvent were lower than those before the management, the differences were statistically significant (P＜0.05).Conclusion The implementation of antimicrobial stewardship can significantly increase the rationality of the use of antimicrobial drugs in the perioperative period of type Ⅰincision surgery, and effectively improve the quality evaluation of the antimicrobial stewardship process, thereby ensuring the safety of patients′ medication.

Key words： Antimicrobial stewardship Type Ⅰincision Surgery Perioperative period Rationality

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	LIU Zhang-sheng
	LIAO Yuan-yue
	LI Jia-hong

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LIU Zhang-sheng,LIAO Yuan-yue,LI Jia-hong. Effect of antimicrobial stewardship on the rationality of antimicrobial use in perioperative period of type Ⅰincision surgery[J]. 中国当代医药, 2020, 27(23): 186-189.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I23/186

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