|
|
Analysis of social function status in patients with schizophrenia and its influencing factors |
LIU Qiu-lan WU Wen-yan |
The Third Department of Inpatient 9th Ward,Ji′an Third People′s Hospital,Jiangxi Province,Ji′an 343100,China |
|
|
Abstract Objective To explore the social function status in patients with schizophrenia and its influencing factors.Methods A total of 76 patients with schizophrenia who received treatment in Ji′an Third People′s Hospital from August 2018 to August 2020 were selected as the research objective.The social function of all patients was evaluated according to the social functional rafing scale(SFRS),and the influencing factors of low social function in patients with schizophrenia were analyzed.Results A total of 76 patents after SFRS assessment,there were 31 patients had low social function,accounting for 40.79%,and 45 patients had good social function,accounting for 59.21%.The results of logistic regression analysis test showed that female (β=3.296,OR=27.000,95%CI=7.514-97.025),hospitalization times ≥3 times (β=3.486,or=32.667,95%CI=9.701-96.684),low degree of disease cognition (β=2.014,OR=15.796,95%CI=4.257-36.740),high score of extravertebral side effects (β=2.749,OR=21.307,95%CI=6.226-53.281)were the risk factors of low social function in patients with schizophrenia(OR>1,P<0.05).The degree of disease cognition(β=-1.074,OR=0.342,95%CI=0.200-0.582)was the protective factor of social function in patients with schizophrenia,the higher the degree of disease cognition,the better the social function of patients(OR>1,P<0.05).Conclusion A part of patients with schizophrenia have low social function,and female,hospitalization times≥3 times,low degree of disease cognition,high score of extravertebral side effects are the risk factors of low social function in patients with schizophrenia,at the same time,the degree of disease cognition is the protective factor of social function,targeted preventive measures can be implemented according to the risk factors in clinic,in order to improve the social function of patients.
|
|
|
|
|
[20] |
王锋,朱长才,朱可,等.精神分裂症家庭照护者心理健康影响因素的结构方程模型分析[J].中华疾病控制杂志,2019,23(2):437-439.
|
[21] |
李素荣,王轶虎.认知行为干预对首发精神分裂症患者自知力及生活质量的影响[J].中国现代医生,2020,58(2):107-110.
|
[22] |
袁素丽,朱春燕.综合心理治疗及干预对康复期精神分裂症患者社会功能的影响[J].中国现代医生,2019,57(26):143-146.
|
[1] |
李晓驷,王克永,董毅,等.安徽省精神分裂症分级诊疗指南[J].安徽医学,2018,39(2):20-23.
|
[2] |
崔洪梅,周燕玲,李冠男,等.长期住院精神分裂症稳定期患者社会功能及影响因素[J].中国神经精神疾病杂志,2018,44(11):37-41.
|
[3] |
Lin C,Lin CH,hang Y,et al.Sodium Benzoate,a D-Amino Acid Oxidase Inhibitor,Added to Clozapine for the Treatment of Schizophrenia:A Randomized,Double-Blind,Placebo-Controlled Trial[J].Biol Psychiatry,2017,13(1):1673-1675.
|
[4] |
张明园.精神分裂症现代诊疗[M].南京:江苏科学技术出版社,2001:1165-1168.
|
[5] |
司天梅,舒良,田成华,等.个体和社会功能量表中文版在精神分裂症患者中的信效度[J].中国心理卫生杂志,2009,23(11):790-794.
|
[6] |
Simpson GM,Angus JW.A rating scale for extrapyramidal side effects[J].Acta Psychiatr Scand Suppl,2010,45(212):11-19.
|
[7] |
刘登堂,岑海欣,江开达,等.2017年中国精神分裂症生物学研究进展(英文)[J].上海精神医学,2018,30(3):9-15.
|
[8] |
王玉花,田野,胡强,等.BDNF基因多态性与精神分裂症发病及临床症状的相关性[J].神经疾病与精神卫生,2019,19(1):48-51.
|
[9] |
Steen V,Skrede S,Polushina T,et al.Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment[J].Eur Neuropsychopharmacol,2017,27(6):589-598.
|
[10] |
王志满,陈薇,贺英,等.绘画心理技术训练辅助抗精神病药物对精神分裂症康复期患者恢复效果的影响[J].中国医师杂志,2020,22(11):1677-1680,1685.
|
[11] |
Krause M,Zhu Y,Schneider-Thoma J,et al.Efficacy,acceptability,and tolerability of antipsychotics in children and adolescents with schizophrenia:A network meta-analysis[J].Eur Neuropsychopharmacol,2018,28(1):948-950.
|
[12] |
陈岗,蒋丹,熊青蓉,等.长病程精神分裂症患者社会功能的影响因素分析[J].四川医学,2017,38(6):660-663.
|
[14] |
张盛夏,罗亮,罗振娟.精神分裂症儿童长程治疗中病情恢复特点及其影响因素分析[J].解放军护理杂志,2018,35(21):6-10.
|
[16] |
刘鹏,陈宽玉,唐小伟,等.首发精神分裂症患者缓解期神经认知功能和社会认知功能的研究[J].临床精神医学杂志,2018,28(1):45-47.
|
[17] |
陈声云,文飞,赵崇邦,等.认知功能缺陷对慢性精神分裂症患者社会功能和生活质量的影响[J].中华医学杂志,2020,100(5):351-356.
|
[18] |
陈声云,夏晓伟,赵崇邦,等.认知功能与稳定期精神分裂症患者服药依从性关系的研究[J].中华神经医学杂志,2019,18(7):668-673.
|
[13] |
Dietsche B,Kircher T,Falkenberg I.Structural brain changes in schizophrenia at different stages of the illness:A selective review of longitudinal magnetic resonance imaging studies[J].Aust N Z J Psychiatry,2017,51(5):1236-1238.
|
[15] |
Oliveri L,Awerbuch AW,Jarskog LF,et al.Depression predicts Self Assessment of Social Function in both patients with schizophrenia and healthy People[J].Psychiatry Res,2019,284(1):1126-1128.
|
[19] |
Lee SJ,Kim KR,Lee SY,et al.Impaired Social and Role Function in Ultra-High Risk for Psychosis and First-Episode Schizophrenia:Its Relations with Negative Symptoms[J].Psychiatry Investig,2017,14(2):186-188.
|
[23] |
李振超,甘郁文,郑小泳.临床路径管理对首发精神分裂症认知功能的影响[J].现代医院,2019,19(9):1272-1274.
|
|
|
|