阴道菌群与宫颈癌发生发展的研究进展

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Abstract Cervical cancer is one of the most common malignant tumors in women, and the vaginal flora plays an important role in the occurrence and development of cervical cancer. Under the action of various risk factors, the number of lactobacilli in the vaginal flora decreases, and anaerobic bacteria replace lactobacilli as the dominant flora, which will lead to the occurrence of bacterial vaginosis, which is conducive to high-risk human papillomavirus persistent infection and cervical epithelium. The internal neoplasia even gradually develops to cervical cancer.This article reviews the relationship between the vaginal flora and the occurrence and development of cervical cancer, and aims to guide the clinical application of gynecology to better and rationally use drugs, maintain the stable balance of vaginal flora, and prevent the occurrence of cervical cancer.

Key words： Vaginal flora Bacterial vaginosis Human papillomavirus infection Cervical cancer

Received: 16 April 2021

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