微通道经皮肾镜碎石术治疗肾结石患者的临床效果及对患者炎症因子的影响

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Abstract Objective To explore the clinical effect of microchannel percutaneous nephrolithotomy in the treatment of patients with kidney stones and its influence on inflammatory factors. Methods A total of 140 patients with kidney stones who were treated with microchannel percutaneous nephrolithotomy and admitted to the Department of Urology,Hunan Aerospace Hospital from September 2017 to September 2019 were selected as the research subjects, and the patients were divided into a control group (n=70) and an observation group (n=70) by computer random drawing method.Patients in the observation group were treated with microchannel percutaneous nephrolithotomy, and patients in the control group were treated with standard-channel percutaneous nephrolithotomy. The clinical indexes, levels of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) and the total incidence of complications were compared between the patients of two groups. Results The operation time of the observation group was longer than that in the control group, the intraoperative blood loss was less than that in the control group, and the bed time and hospital stay were shorter than that in the control group, the differences were statistically significant (P<0.05). Before treatment, the IL-6 and TNF-α levels of patients in the two groups were compared, and the differences were not statistically significant (P>0.05). After treatment, the levels of IL-6 and TNF-α in the two groups were higher than those before treatment, and the levels of IL-6 and TNF-α in the observation group were lower than those in the control group, with statistical significances (P<0.05). During the treatment, the total incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion For patients with kidney stones, the use of microchannel percutaneous nephrolithotomy can obtain better effects than traditional standard channel operation. It can effectively shorten the operation time, reduce the surgical trauma of the patient and accelerate the recovery of the patient. Meanwhile, the reduction of surgical wounds can alleviate the inflammatory stress response of patients, and also reduce the probability of postoperative complications in patients, which has the value of promotion and application.

Key words： Microchannel percutaneous nephrolithotomy Kidney stones Inflammatory factors Clinical efficacy

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HUANG Bao-qing. Clinical effect of microchannel percutaneous nephrolithotomy in the treatment of patients with kidney stones and its influence on inflammatory factors[J]. 中国当代医药, 2021, 28(34): 109-112.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I34/109

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