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| Clinical effect of Liangxue Xiaobi Decoction combined with Calcipotriol Betamethasone Ointment in the treatment of psoriasis vulgaris |
| LU Jian-xiang SONG Dan-yang LI Shang-yun▲ |
| Department of Dermatology, Shenyang Seventh People′s Hospital, Liaoning Province, Shenyang, 110003, China |
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Abstract Objective To study the curative effect of Liangxue Xiaobi Decoction combined with Calcipotriol Betamethasone Ointment in the treatment of psoriasis vulgaris. Methods A total of 100 patients with psoriasis vulgaris admitted to the Seventh People′s Hospital of Shenyang from October 2019 to October 2020 were selected as the research objects and randomly divided into the observation group（50 cases） and the control group（50 cases）. The observation group was treated with Liangxue Xiaobi Decoction combined with Calcipotriol Betamethasone Ointment, and the control group was treated with Calcipotriol Betamethasone Ointment. The psoriasis severity index （PASI）, visual analogue scale （VAS）, C-reactive protein （CRP）, serum interleukin-6 （IL-6）, quality of life and total effective rate of treatment were compared between the two groups. Results The PASI score and VAS score of the observation group after treatment were lower than those of the control group, the differences were statistically significant （P＜0.05）; the levels of CRP and IL-6 in the observation group after treatment were lower than those in the control group, and the differences were statistically significant （P＜0.05）; the observation group′s physical domain, psychological domain, social domain,material life score and the total effective rate of treatment were higher than those of the control group, and the differences were statistically significant （P＜0.05）. Conclusion Liangxue Xiaobi Decoction combined with Calcipotriol Betamethasone Ointment has a significant effect in the treatment of psoriasis vulgaris, and can reduce the level of inflammatory factors, improve the treatment effect and improve the prognosis of patients.
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