记忆门诊“环路式体系”对阿尔茨海默病管理的应用效果

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Abstract Objective To explore the effect of application of the loop system in memory clinic on Alzheimer′s disease management.Methods A retrospective analysis was performed on the clinical data of 298 patients diagnosed with Alzheimer′s disease who were admitted to the Department of Neurology of Guangzhou First People′s Hospital for the first time before the implementation of "loop system"(from January 2017 to December)and after the implementation of "loop system"(from January 2020 to December).Patients first diagnosed from January 2020 to December were included in the study group (179 cases),and patients first diagnosed from January 2017 to December were included in the control group (119 cases).According to the relevant guidelines and consensus at home and abroad,a loop system consisting of community,outpatient screening and diagnosis,comprehensive intervention and return to the community was formed as a comprehensive management mode through standardizing the memory clinic management system,in combination with their own characteristics.The rate of patients who selected memory clinic for the first visit,severity of dementia,completion rates of auxiliary examination and related assessment scales were compared between the two groups.Results The rate of patients who selected memory clinic for the first visit of study group was higher than that in the control group,with statistically significant difference(P＜0.05).The proportion of mild cognitive impairment in study group was higher than that in control group,and the difference was statistically significant(P＜0.05).The completion rate of blood test package,neuropsychiatric inventory (NPI),Montreal cognitive assessment(MoCA),activity of daily living scale (ADL),the delivery rate of cerebrospinal fluid biomarkers were higher than those in the control group,the differences were statistically significant(P＜0.05).There were no significant difference in the completion rates of imaging examination,mini-mental state examination(MMSE),Hamilton anxiety scale(HAMA)and Hamilton depression scale (HAMD)between the two groups(P＞0.05).Conclusion The "loop system" of memory clinic can promote the early screening and standardized diagnosis and treatment of diseases,especially the advancement of disease intervention.

Key words： Cognitive impairment Alzheimer&prime s disease Mild cognitive impairment Memory clinic Administration

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	GUO Ai-hua
	PAN Xiao-ping

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GUO Ai-hua,PAN Xiao-ping. Effect of application of the loop system in memory clinic on Alzheimer's disease management[J]. 中国当代医药, 2021, 28(31): 74-77转81.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I31/74

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