四君子汤联合西药治疗对烧伤患者炎症反应及康复的影响

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Abstract Objective To explore the effect of Sijunzi Decoction combined with Western medicine on inflammatory reaction and rehabilitation of burn patients.Methods A total of 64 burn patients admitted to the Second Department of Surgery,Guixi Hospital of Traditional Chinese Medicine from January 2018 to December 2019 were selected as the research subjects.They were divided into the control group and the study group by random number table method,with 32 patients in each group.The control group was treated with Western medicine,and the study group was treated with Sijunzi Decoction on the basis of the control group.The clinical efficacy,traditional Chinese medicine syndrome score before and after treatment,serum inflammatory factor(interleukin-2[IL-2],interleukin-6[IL-6],interleukin-10[IL-10],tumor necrosis factor-α[TNF-α])levels and adverse reactions were compared between the two groups.Results The total effective rate of the study group was 93.75%,higher than 50.00% of the control group,and the difference was statistically significant(P<0.05).After treatment,the traditional Chinese medicine syndrome score of the study group was(3.77±0.84)points,lower than(7.92±0.86)points of the control group,and the difference was statistically significant(P<0.05).After treatment,the level of IL-6 in the study group was(202.16±17.54)mg/L,and the level of TNF-α was(38.90±13.06)mg/L,which were lower than those in the control group([232.64±16.31],[57.24±12.13]mg/L),IL-2 level was(5.19±0.93)mg/L,IL-10 level was(90.42±6.73)mg/L in the study group,which were higher than those in the control group([4.31±0.85),[85.43±6.17]mg/L),and the differences were statistically significant(P<0.05).There were no serious adverse reactions in the two groups.Conclusion Sijunzi Decoction combined with Western medicine in the treatment of burn can effectively relieve the clinical symptoms and regulate the levels of inflammatory factors without serious adverse reactions.

Key words： Burn Sijunzi Decoction Ulinastatin Inflammatory factors Adverse reactions

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	Articles by authors
	GAO Ming-long
	ZHENG Kai
	LIU Yu-yu

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GAO Ming-long,ZHENG Kai,LIU Yu-yu. Effect of Sijunzi Decoction combined with Western medicine on inflammatory reaction and rehabilitation of burn patients[J]. 中国当代医药, 2021, 28(22): 201-204.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I22/201

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