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| Research on the relationship between serum 25(OH)D3 level and metabolic syndrome in middle-aged and elderly people in Hulunbuir area |
| DING Li-ping1 SONG Li-gang1 LI Yi-xin2 LIU Zi-qi1 ZHOU Ming-shuang1 ZHOU Fei1 ZHANG Xue |
1.Department of Endocrinology,Hulunbuir People′s Hospital(Hulunbuir Clinical Medical College,Inner Mongolia University for Nationalities),Inner Mongolia Autonomous Region,Hulunbuir 021008,China;
2.Department of Laboratory Medicine,Hulunbuir People′s Hospital(Hulunbuir Clinical Medical College,Inner Mongolia University for Nationalities),Inner Mongolia Autonomous Region,Hulunbuir 021008,China |
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Abstract Objective To explore the relationship between serum 25-hydroxyvitamin D3[25(OH)D3]levels and metabolic syndrome(MS)in the elderly in Hulunbuir area.Methods A total of 2145 MS patients who were admitted to the Hulunbuir People′s Hospital of Inner Mongolia from January 2017 to August 2019 were selected as the observation group,and 684 non-MS patients treated in Hulunbuir People′s Hospital of Inner Mongolia during the same period were selected as the control group.The body mass index(BMI),systolic blood pressure,diastolic blood pressure,blood biochemical indexes[25(OH)D3,total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),fasting blood glucose(FBG),uric acid(UA),and glycated hemoglobin(HbA1c)]were compared between the two groups,the correlation between 25(OH)D3 in the observation group and BMI,systolic blood pressure,diastolic blood pressure and blood biochemical indexes was analyzed,and the 25(OH)D3 levels in the two groups were compared.Results The BMI,LDL-C,TC,TG,HbA1c,FBG,systolic blood pressure and diastolic blood pressure of in observation group were higher than those in control group,and 25(OH)D3 was lower than that in the control group,the differences were statistically significant(P<0.05); There were no significant differences in HDL-C and UA between the two groups(P>0.05).The 25(OH)D3 level in the observation group was negatively correlated with BMI,HbA1c,FBG,diastolic blood pressure,LDL-C and systolic blood pressure(P＜0.05).The proportions of 25(OH)D3≤20 ng/mL and >20～30 ng/mL in observation group were higher than those in control group,and the proportions of 25(OH)D3> 30 ng/mL were lower than those in control group,the differences were statistically significant(P<0.05).Conclusion The serum 25(OH)D3 level is relatively insufficient in the middle-aged and elderly MS patients in Hulunbuir area,and its level is closely related to BMI,HbAlc,FBG,diastolic blood pressure,LDL-C,and systolic blood pressure.The decrease of 25(OH)D3 level may be related to MS Happened related.
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| [1] |
孟苹花，魏芳，王喆，等.低水平维生素D 与维持性血液透析患者代谢综合征的关系[J].中华肾脏病杂志，2018，34（1）：10-16.
|
| [2] |
闫慧敏，张梅，张笑，等.中国老年人代谢综合征流行特征及其影响因素研究[J].中华高血压杂志，2019，27（11）：110.
|
| [3] |
夏莉莉，汤瑜斌，蒋小红.老年2 型糖尿病病人25（OH）D3水平与尿蛋白排泄率的相关性[J].实用老年医学，2018，32（1）：30-33.
|
| [4] |
廖鑫，张琳，张晗，等.多囊卵巢综合征患者血清25（OH）D3与糖脂代谢的相关性研究[J].中国骨质疏松杂志，2017，23（10）：1300-1303，1308.
|
| [5] |
付俊玲，候聪，韩兰稳，等.北京地区青年人群血清维生素D水平及其与糖代谢的关系[J].中华骨质疏松和骨矿盐疾病杂志，2017，10（3）：216-221.
|
| [6] |
王为波，武丽，季聪华，等.社区老年人群代谢综合征患病率及3 种诊断标准的一致性[J].浙江医学，2016，38（8）：565-567.
|
| [7] |
林涛，王栋，黄立坤.运动及饮食干预对农村居民代谢综合征患者糖脂代谢的影响[J].中国药物与临床，2017，17（1）：141.
|
| [8] |
朱晓云，王春霞，赵玉雪，等.代综方改善38 例代谢综合征糖脂代谢异常的临床研究[J].辽宁中医杂志，2017，44（9）：1881-1885.
|
| [9] |
孙许龙，朱利勇，李鹏洲，等.减重代谢外科中的维生素D缺乏及其影响[J].国际外科学杂志，2017，44（5）：344-349.
|
| [10] |
岳晓玲，战芳，张谦.维生素D 对体重指数正常妊娠期糖尿病孕妇的血糖控制及妊娠结局的影响[J].中国当代医药，2019，26（8）：99-102.
|
| [11] |
李京京，陶瑞雪，张英，等.孕期维生素D、甲状旁腺素水平与糖代谢功能的关联研究[J].中华内分泌代谢杂志，2019，35（4）：307-313.
|
| [12] |
杨姣姣，王艳红，邹楠，等.山西人群维生素D 水平与2型糖尿病的相关性研究[J].东南大学学报（医学版），2019，38（4）：628-632.
|
| [13] |
葛秋霞，蒋理，唐未名，等.血清25-羟维生素D3水平与肥胖的相关性研究[J].国际免疫学杂志，2019，42（1）：32-37.
|
| [14] |
高伟，费扬帆，王椿，等.血清25-羟维生素D3水平与糖代谢的相关性研究[J].四川大学学报（医学版），2017，48（1）：81-85.
|
| [15] |
蔡穗珍，陈家卫，陈美银.不同糖代谢人群血清25（OH）D3水平分析及相关研究[J].福建医药杂志，2017，39（1）：81-84.
|
| [16] |
张熙曦，黄桂英，王芳，等.多囊卵巢综合征患者维生素D 营养状态与糖脂代谢的临床关系及对妊娠结局的影响[J].中国计划生育和妇产科，2019，11（6）：8-12.
|
|
|
|
