阿司匹林与小剂量阿加曲班治疗急性脑梗死的效果比较

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Abstract Objective To compare the effect between Aspirin and low-dose Argatroban in the treatment of acute cerebral infarction.Methods From January 2017 to December 2019,90 patients with acute cerebral infarction admitted to the Iron Coal General Hospital of China Resources Liaojian Group were selected as the research objects.They were divided into group A and group B according to random number table method,with 45 cases in each group.On the basis of basic treatment,group A was treated with low-dose Argatroban,and group B was treated with Aspirin.The treatment course of both groups was 7 days.The clinical efficacy,the National Institutes of Health stroke scale(NIHSS)score and Barthel index score before and after treatment,the incidence of adverse reactions were compared between the two groups.Results The NIHSS scores of the two groups after treatment were lower than those before treatment,and the Bathel index of the two groups after treatment were higher than those before treatment,the differences were statistically significant(P<0.05).The NIHSS score of group A after treatment was lower than that of group B,and the Bathel index of group A after treatment was higher than that of group B,the differences were statistically significant(P<0.05).The total effective rate of group A was higher than that of group B,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Compared with Aspirin,low-dose Argatroban has better curative effect in the treatment of acute cerebral infarction,which has significant effect on improving the neurological function of patients and enhancing the ability of life autonomy,and is suitable for promotion.

Key words： Aspirin Argatroban Acute cerebral infarction

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YE Feng. Comparision effect between Aspirin and low-dose Argatroban in the treatment of acute cerebral infarction[J]. 中国当代医药, 2021, 28(22): 114-116.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I22/114

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