某院送检女性患者泌尿生殖道样本生殖道病原体感染情况分析

Abstract
Figure/Table
References (16)
Related Citation (7)

Download: PDF (0 KB) HTML (33 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To analyze the pathogen infection in female reproductive tract samples from outpatients and inpatients in the First Affiliated Hospital of Fujian Medical University.Methods A total of 417 female reproductive tract pathogens nucleic acid samples were collected from outpatients and inpatients of the First Affiliated Hospital of Fujian Medical University from December 2020 to February 2021, and the nucleic acid test results and clinical data of these samples were analyzed.The pathogens include Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), Mycoplasma genitalium (MG), Mycoplasma hominis (MH), herpes simplex virus typeⅡ(HSV-Ⅱ), Ureaplasma urealyticum (UU) and Ureaplasma parvum (UP), the infection status of the patient were analyzed.Results Among 417 patients, 230 (55.2%)were positive for pathogen nucleic acid.The positive rate of nucleic acid of seven pathogens was statistically significant(P＜0.05), and the positive rate of UP was the highest (38.1%).There was no significant difference in the positive rate of pathogen nucleic acid among female patients of different ages (P＞0.05).The positive rate of pathogen nucleic acid in patients with different clinical symptoms was significantly different (P＜0.05), among which the positive rate of gynecological tumor and urinary and reproductive system infection was higher, 72.4% and 71.3%, respectively.Eighty-two women were infected with two or more pathogens at the same time, with a maximum of six pathogens at the same time.Conclusion With the continuous development of diagnostic technology, molecular diagnosis has been widely used in clinical practice, including DNA detection and RNA detection, which provide a better method for the diagnosis of these pathogens and can provide richer information for clinical diagnosis and treatment.It is necessary to pay attention to the mixed infection of common pathogens in the female reproductive system and strengthen prevention and screening.

Key words： Reproductive tract infection Nucleic acid detection Ureaplasma urealyticum Ureaplasma parvum

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	WANG Xiang-rong

Cite this article:

WANG Xiang-rong. Analysis of genitourinary tract pathogen infection of female patients in a hospital[J]. 中国当代医药, 2021, 28(29): 174-177.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I29/174

[1]	Magnus U，Catriona S，Jane S，et al.Sexually transmitted infections：challenges ahead[J].Lancet Infect Dis，2017，17（8）：e235-e279.
[2]	王千秋，刘全忠，徐金华.性传播疾病临床诊疗与防治指南[M].上海：上海科学技术出版社，2014.
[3]	楼扬锋，李瑞鹏，诸靖宇，等.15 305 例门急诊患者淋球菌，沙眼衣原体及解脲脲原体感染情况分析[J].浙江医学，2019，41（7）：680-682.
[4]	李平卫，赵红英，赵缜，等.女性泌尿生殖道感染患者解脲脲原体，微小脲原体与沙眼衣原体感染情况分析[J].中国皮肤性病学杂志，2019，263（8）：66-69.
[5]	孟凡亮，李晶，龚杰，等.解脲脲原体和微小脲原体相对定量荧光PCR 方法的建立及应用[J].中国病原生物学杂志，2020，15（12）：1422-1426.
[6]	吉秀家，王艳波，李芳，等.兰州市育龄妇女的生殖道感染状况及相关影响因素分析[J].中国妇幼保健，2019，34（18）：4274-4276.
[7]	魏菁菁，王冬梅，丁进亚，等.武汉地区1522 例泌尿生殖系统支原体感染情况及耐药性分析[J].中国医药科学，2020，10（22）：1-4，8.
[8]	张蕾，陈锐，王颖，等.不同方法检测女性生殖道病原微生物感染的比较研究[J].中国实用妇科与产科杂志，2020，36（10）：1001-1006.
[9]	Cunningham SA，Mandrekar JN，Rosenblatt JE，et al.Rapid PCR Detection of Mycoplasma hominis，Ureaplasma urealyticum，and Ureaplasma parvum[J].Int J Bacteriol，2013（5）：168742.
[10]	张岱，刘朝晖.生殖道支原体感染诊治专家共识[J].中国性科学，2016，25（3）：80-82.
[11]	章黎.女性生殖道UP、UU 及CT 感染情况及细菌耐药性分析[J].中国妇幼保健，2020，35（19）：3653-3656.
[12]	刘久磊.HR-HPV、CT、NG、UU DNA PCR 联合阴道微生态检测对宫颈癌筛查的研究[J].世界最新医学信息文摘，2020，20（50）：167-168，170.
[13]	汪蕾，蔡惠，杨霞，等.性传播病原体隐性感染与高危型HPV 及宫颈病变的相关性[J].西安交通大学学报（医学版），2020，41（4）：577-582.
[14]	陈永兰.高危型人乳头瘤病毒感染者生殖道解脲支原体感染情况分析及其与宫颈组织学改变的关系探讨[J].中国妇幼保健，2019，34（24）：5610-5613.
[15]	赵连爽，马国强，米玲，等.下生殖道常见性传播病原体检测及其与HPV 感染和子宫颈上皮内瘤变的相关性[J].中国实用妇科与产科杂志，2020，36（5）：457-461.
[16]	钟继生，曾云，张丽雅.实时荧光核酸恒温扩增技术检测泌尿生殖道生殖支原体感染的临床效果[J].检验医学与临床，2020，17（15）：2204-2206.