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| Research on the relationship between urinary red blood cell morphology and traditional Chinese medinine syndrome types in patients with purpuric nephritis |
| LUO Li-yuan ZHONG Ying-chao XIE Yue-heng ZHONG Hua-wen |
| The Second Department of Internal Medicine, Yangjiang Hospital of Traditional Chinese Medicine |
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Abstract Objective To observe the relationship between urinary red blood cell morphology and traditional Chinese medinine (TCM) syndrome types in patients with purpuric nephritis.Methods A total of 100 patients with purpuric nephritis in Yangjiang Hospital of Traditional Chinese Medicine from August 2020 to March 2021 were selected as the research objects, 10 ml of fresh mid-stage urine from the patients was collected, and urinary red blood cell morphology examination was performed, combined with the patient′s tongue, pulse, and syndrome characteristics.The patients were classified into syndrome differentiation, and the relationship between urinary red blood cell morphology and TCM syndrome types in patients with purpuric nephritis was explored.Results According to the differentiation of TCM syndromes, 100 patients had apoplexy and heat stroke syndrome in 20 cases (20.0%), heat toxin internal burning syndrome in 12 cases (12.0%), dampness and blood stasis mutual syndrome in 23 cases (23.0%), Qi and Yin deficiency syndrome 36 cases (36.0%), 9 cases (9.0%) of spleen and kidney yang deficiency syndrome; the percentage of abnormal red blood cells and the percentage of spiny red blood cells in patients with deficiency of both qi and yin syndrome were significantly higher than those of other TCM syndrome types, and the differences were statistically significant (P＜0.05).The percentage of abnormal red blood cell content of Qi and Yin deficiency syndrome: target red blood cells＞positive red blood cells＞circular red blood cells＞others＞small red blood cells＞macro red blood cells＞spinous red blood cells, the comparison of red blood cell morphology, and the differences were statistically significant (P＜0.05).The percentage of ring red blood cells in the syndrome of dampness and stasis＞positive erythrocytes＞small red blood cells＞target erythrocytes ＞macro erythrocytes ＞others ＞spinous erythrocytes, and the differences were statistically significant(P＜0.05).The percentage of abnormal erythrocyte content in wind-heat syndrome: small erythrocytes＞erythrocytes＞target erythrocytes＞other ＞ring red blood cells＞macro red blood cells＞acchinoid red blood cells, and the differences were statistically significant (P＜0.05).Percentage of positive red blood cell morphology content in spleen and kidney yang deficiency syndrome＞others＞small red blood cells＞macro red blood cells＞target red blood cells＞ring red blood cells＞spinous red blood cells, and the differences were statistically significant (P＜0.05).The circular red blood cells of the fever syndrome＞positive red blood cells＞others＞target red blood cells＞macro red blood cells＞small red blood cells＞spinous red blood cells, and the differences were statistically significant (P＜0.05).Conclusion TCM syndromes of patients with purpuric nephritis are mostly qi and yin deficiency, and the percentage of abnormal red blood cell content of different TCM syndromes also shows significant differences.The detection of urine red blood cell morphology has important reference significance in TCM syndrome differentiation.
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