|
|
Related factors of chronic renal failure combined with upper gastrointestinal hemorrhage and its relationship with gastrin-17,pepsinogen I and pepsinogen Ⅱ |
LI Yong-qiang1 ZOU Yang2 WANG Ling3 WANG Jia-fang |
1.Department of Internal Medicine,Kangning Hospital of Jiangxi,Jiangxi Province,Nanchang 330100,China;
2.Department of Function,Nanchang Hongdu Hospital of TCM,Jiangxi Province,Nanchang 330100,China;
3.Department of Geriatrics,Kangning Hospital of Jiangxi,Jiangxi Province,Nanchang 330100,China;
4.Department of Gastroenterology,Kangning Hospital of Jiangxi,Jiangxi Province,Nanchang 330100,China |
|
|
Abstract Objective To explore the related factors of chronic renal failure(CRF)combined with upper gastrointestinal hemorrhage(UGH)and its relationship with gastrin-17(G-17),pepsinogen Ⅰ(PG-Ⅰ)and pepsinogen Ⅱ(PG-Ⅱ).Methods The clinical data of 80 CRF patients admitted to Kangning Hospital of Jiangxi from June 2019 to December 2020 were retrospectively analyzed.According to presence or absence of UGH symptoms,they were divided into UGH group(33 cases)and non-UGH group(47 cases).The clinical data(including the gender,age,G-17,PG-Ⅰ/PG-Ⅱ,usage of unfractionated heparin or not,and stress ulcer or not)were compared between the two groups,and the related factors of UGH were analyzed.Results The results of univariate analysis showed that the differences in the age,G-17,PG-Ⅰ,PG-Ⅱ,PG-Ⅰ/PG-Ⅱ,usage of unfractionated heparin,and stress ulcer between the two groups were statistically significant(P<0.05).The results of multivariate analysis showed that G-17,PG-Ⅰ/PG-Ⅱand stress ulcer were correlative factors of CRF combined with UGH(P<0.05). Spearman correlation analysis showed that G-17,PG-Ⅰand PG-Ⅱwere positively correlated with CRF combined with UGH(r=0.614,0.582,0.591, P<0.05).Conclusion G-17,PG-Ⅰ/PG-Ⅱand stress ulcer are risk factors of CRF combined with UGH,and G-17,PG-Ⅰand PG-Ⅱare significantly related to CRF combined with UGH.
|
|
|
|
|
[1] |
揭乐琴,柳亿,张孝亮,等.慢性肾功能不全患者医院感染病原菌特点及影响因素分析[J].中华医院感染学杂志,2018,28(6):863-865,875.
|
[2] |
王旭东,宋坚,张芬,等.肾安方联合西医常规治疗早中期慢性肾功能不全临床研究[J].中国中医药信息杂志,2019,26(2):20-25.
|
[3] |
李涛,李小帆.肾康栓联合肾衰宁片治疗慢性肾功能不全疗效及其对血清CRP,ADPN 的影响[J].西部中医药,2020,33(3):94-96.
|
[4] |
邢忠海,邱巍,张秀香,等.慢性肾功能不全患者甲状旁腺素,钙磷测定的临床研究[J].检验医学与临床,2019,16(2):79-81.
|
[5] |
赵遇迎.舒适护理模式在上消化道出血患者护理中的应用[J].实用临床医药杂志,2018,22(6):33-35.
|
[6] |
林凡榆,黄华,王家平,等.上消化道出血临床评分系统的应用及研究进展[J].昆明医科大学学报,2019,40(8):120-125.
|
[7] |
刘晓菊.预见性护理模式对高龄上消化道出血患者舒适度、并发症及护理满意度的影响[J].河北医药,2018,40(8);144-147.
|
[8] |
游洁玉,姜娜.儿童非静脉曲张性上消化道出血的内镜下诊治进展[J].中国实用儿科杂志,2018,33(11):34-37.
|
[9] |
陈景荷,张艳琴,王宏斌.泮托拉唑预防慢性肾功能衰竭并发上消化道出血的疗效分析[J].中国医药导刊,2016,18(6):621-622.
|
[10] |
陆再英,钟南山.内科学[M].北京:人民卫生出版社,2009:549.
|
[11] |
《中华内科杂志》编辑委员会,《中华医学杂志》编辑委员会,《中华消化杂志》编辑委员会,等.急性非静脉曲张性上消化道出血诊治指南(2018年,杭州)[J].中华内科杂志,2019,58(3):173-180.
|
[12] |
柏愚,李延青,任旭,等.应激性溃疡防治专家建议(2018版)[J].中华医学杂志,2018,98(42):3392-3395.
|
[13] |
韦德芳.生长抑素联合泮托拉唑对急性非静脉曲张性上消化道出血患者凝血功能及血液流变学的影响[J].国际消化病杂志,2018,38(2):65-68.
|
[14] |
向红雨,周中银.探讨不同性别非静脉曲张上消化道出血在重症病房的临床特点[J].胃肠病学和肝病学杂志,2019,28(1):75-78.
|
[15] |
朱健康,艾克帕尔·艾肯,王义霞,等.喀什地区维吾尔族与汉族人群上消化道出血的流行病学和病因演变[J].中华消化杂志,2020,40(12):874-877.
|
[16] |
沈雯雯,张玫,和芳.北京部分地区10年中青年和老年上消化道出血病因流行病学分析及经济负担研究[J].中国临床医生杂志,2018,46(12):1402-1406.
|
[17] |
刘晶晶,崔静,王颖,等.放大窄带成像和血清学检测对萎缩性胃炎诊断的对比性评估[J].中国现代医生,2021,59(1):40-43,193.
|
[18] |
吴峰,周正钱,刘增勇,等.PG Ⅰ、PG Ⅱ、G-17 检测在胃癌及萎缩性胃炎诊断中的应用价值[J].中国当代医药,2019,26(5):86-88.
|
[19] |
胡晓华,张震,李万红,等.胃蛋白酶原及胃泌素比值评分对重度萎缩性胃炎的判断价值[J].中国现代医生,2019,57(2):21-24,28.
|
[20] |
董智平,赵江蓉,张旋,等.胃黏膜“血清学活检”在不同胃部疾病中的表达及意义[J].中国中西医结合外科杂志,2019,25(4):47-51.
|
[21] |
卢慧,张敏,张家庆,等.胃蛋白酶原水平与血液透析并发上消化道出血的关系研究[J].安徽医学,2019,40(2):137-140.
|
[22] |
王峰,李丽丽.维持性血液透析患者消化道出血的相关因素分析[J].江苏医药,2018,44(8):919-922.
|
|
|
|