拉曼光谱技术识别不同病因脓毒症的潜力

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Abstract Sepsis is a fatal organ dysfunction caused by dysregulation of host response caused by severe infection,which has become a prominent public health problem worldwide and one of the major diseases leading to patient death in the world.At present, the biomarkers commonly used to assist in the diagnosis of sepsis in clinical practice include procalcitonin (PCT), C-reactive protein (CRP) and peripheral white blood cells (WBC), but the above detection items have the disadvantages of time-consuming, labor-intensive and resource-consuming, it cannot quickly identify the cause of sepsis, and even delay the time for patients to receive effective treatment.As a new detection technology based on molecular level, Raman spectroscopy has the advantages of fast speed, high efficiency and strong specificity, which shows strong analytical potential and development space in rapidly identifying the cause of sepsis, it can provide many valuable molecular information for the auxiliary diagnosis and effective treatment of sepsis patients, and better help clinicians to make timely and effective management of them.In this paper, the research results of new molecular detection techniques in recent years are reviewed.

Key words： Raman spectrum Sepsis Molecular testing Biomarkers

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	DU Jin
	XIA Shu-Xiang

Cite this article:

DU Jin,XIA Shu-Xiang. Potential of Raman spectroscopy to identify sepsis of different etiologies[J]. 中国当代医药, 2021, 28(29): 39-42.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I29/39

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