[1] |
Torre LA,Bray F,Siegel RL,et al.Global cancer statistics,2012[J].CA Cancer J Clin,2015,65(2):87-108.
|
[2] |
Nelson ER.The significance of cholesterol and its metabolite,27-hydroxycholesterol in breast cancer[J].Mol Cell Endocrinol,2018,466:73-80.
|
[3] |
Melvin JC,Holmberg L,Rohrmann S,et al.Serum lipid profiles and cancer risk in the context of obesity:Four Metaanalyses[J].J Cancer Epidemiol,2013,2013:823-849.
|
[4] |
Nelson ER,Chang CY,McDonnell DP.Cholesterol and breast cancer pathophysiology[J].Trends Endocrinol Metab,2014,25(12):649-655.
|
[5] |
Hu J,La Vecchia C,de Groh M,et al.Dietary cholesterol intake and cancer[J].Ann Oncol,2012,23(2):491-500.
|
[6] |
Danilo C,Frank PG.Cholesterol and breast cancer development[J].Curr Opin Pharmacol,2012,12(6):677-682.
|
[12] |
Murai T.Cholesterol lowering:role in cancer prevention and treatment[J].Biol Chem,2015,396(1):1-11.
|
[7] |
Kucharska-Newton AM,Rosamond WD,Mink PJ,et al.HDLcholesterol and incidence of breast cancer in the ARIC cohort study[J].Ann Epidemiol,2008,18(9):671-677.
|
[8] |
Ha M,Sung J,Song YM.Serum total cholesterol and the risk of breast cancer in postmenopausal Korean women[J].Cancer Causes Control,2009,20(7):1055-1060.
|
[9] |
Kitahara CM,Berrington de González A,Freedman ND,et al.Total cholesterol and cancer risk in a large prospective study in Korea[J].J Clin Oncol,2011,29(12):1592-1598.
|
[10] |
Gupta RK,Patel AK,Kumari R,et al.Interactions between oxidative stress,lipid profile and antioxidants in breast cancer:a case control study[J].Asian Pac J Cancer Prev,2012,13(12):6295-6298.
|
[11] |
Li C,Yang L,Zhang D,Jiang W.Systematic review and meta-analysis suggest that dietary cholesterol intake increases risk of breast cancer[J].Nutr Res,2016,36(7):627-635.
|
[13] |
Llaverias G,Danilo C,Mercier I,et al.Role of cholesterol in the development and progression of breast cancer[J].Am J Pathol,2011,178(1):402-412.
|
[14] |
Pfefferle AD,Herschkowitz JI,Usary J,et al.Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts[J].Genome Biol,2013,14(11):R125.
|
[15] |
Alikhani N,Ferguson RD,Novosyadlyy R,et al.Mammary tumor growth and pulmonary metastasis are enhanced in a hyperlipidemic mouse model[J].Oncogene,2013,32(8):961-967.
|
[16] |
Nelson ER,Wardell SE,Jasper JS,et al.27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology[J].Science,2013,342(6162):1094-1098.
|
[17] |
Llaverias G,Escolà-Gil JC,Lerma E,et al.Phytosterols inhibit the tumor growth and lipoprotein oxidizability induced by a high-fat diet in mice with inherited breast cancer[J].J Nutr Biochem,2013,24(1):39-48.
|
[18] |
He S,Nelson ER.27-Hydroxycholesterol,an endogenous selective estrogen receptor modulator[J].Maturitas,2017,104:29-35.
|
[19] |
Capasso I,Esposito E,Pentimalli F,et al.Metabolic syndrome affects breast cancer risk in postmenopausal women:National Cancer Institute of Naples experience[J].Cancer Biol Ther,2010,10(12):1240-1243.
|
[20] |
Marwarha G,Raza S,Hammer K,et al.27-hydroxycholesterol:A novel player in molecular carcinogenesis of breast and prostate cancer[J].Chem Phys Lipids,2017,207(Pt B):108-126.
|
[21] |
Bovenga F,Sabbà C,Moschetta A.Uncoupling nuclear receptor LXR and cholesterol metabolism in cancer[J].Cell Metab,2015,21(4):517-526.
|
[22] |
Wu Q,Ishikawa T,Sirianni R,et al.27-Hydroxycholesterol promotes cell-autonomous,ER-positive breast cancer growth[J].Cell Rep,2013,5(3):637-645.
|
[23] |
Gazzerro P,Proto MC,Gangemi G,et al.Pharmacological actions of statins:a critical appraisal in the management of cancer[J].Pharmacol Rev,2012,64(1):102-146.
|
[24] |
Islam MM,Yang HC,Nguyen PA,et al.Exploring association between statin use and breast cancer risk:an updated meta-analysis[J].Arch Gynecol Obstet,2017,296(6):1043-1053.
|
[25] |
Undela K,Srikanth V,Bansal D.Statin use and risk of breast cancer:a meta-analysis of observational studies[J].Breast Cancer Res Treat,2012,135(1):261-269.
|
[26] |
Ahern TP,Pedersen L,Tarp M,et al.Statin prescriptions and breast cancer recurrence risk:a Danish nationwide prospective cohort study[J].J Natl Cancer Inst,2011,103(19):1461-1468.
|
[27] |
Kwan ML,Habel LA,Flick ED,et al.Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors[J].Breast Cancer Res Treat,2008,109(3):573-579.
|
[28] |
Sakellakis M,Akinosoglou K,Kostaki A,et al.Statins and risk of breast cancer recurrence[J].Breast Cancer(Dove Med Press),2016,8:199-205.
|
[29] |
Chae YK,Valsecchi ME,Kim J,et al.Reduced risk of breast cancer recurrence in patients using ACE inhibitors,ARBs,and/or statins[J].Cancer Invest,2011,29(9):585-593.
|
[30] |
Bjarnadottir O,Romero Q,Bendahl PO,et al.Targeting HMGCoA reductase with statins in a window-of-opportunity breast cancer tria[J].Breast Cancer Res Treat,2013,138(2):499-508.
|
[31] |
Shaitelman SF,Stauder MC,Allen P,et al.Impact of Statin Use on Outcomes in Triple Negative Breast Cancer[J].J Cancer,2017,8(11):2026-2032.
|
[32] |
Denoyelle C,Vasse M,Korner M,et al.Cerivastatin,an inhibitor of HMG-CoA reductase,inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines:an in vitro study[J].Carcinogenesis,2001,22(8):1139-1148.
|
[40] |
Rogers TL,Holen I.Tumour macrophages as potential targets of bisphosphonates[J].J Transl Med,2011,9:177.
|
[33] |
Mast N,Lin JB,Pikuleva IA.Marketed Drugs Can Inhibit Cytochrome P450 27A1,a Potential New Target for Breast Cancer Adjuvant Therapy[J].Mol Pharmacol,2015,88(3):428-436.
|
[34] |
Wu Y,Yu DD,Yan DL,et al.Liver X receptor as a drug target for the treatment of breast cancer[J].Anticancer Drugs,2016,27(5):373-382.
|
[35] |
Elangovan S,Pathania R,Ramachandran S,et al.The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival[J].Cancer Res,2014,74(4):1166-1178.
|
[36] |
Lukasova M,Malaval C,Gille A,et al.Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells[J].J Clin Invest,2011,121(3):1163-1173.
|
[37] |
Vini R,Juberiya AM,Sreeja S.Evidence of pomegranate methanolic extract in antagonizing the endogenous SERM,27-hydroxycholesterol[J].IUBMB Life,2016,68(2):116-121.
|
[38] |
Samavat H,Newman AR,Wang R,et al.Effects of green tea catechin extract on serum lipids in postmenopausal women:a randomized,placebo-controlled clinical trial[J].Am J Clin Nutr,2016,104(6):1671-1682.
|
[39] |
Young RJ,Coleman RE.Zoledronic acid to prevent and treat cancer metastasis:new prospects for an old drug[J].Future Oncol,2013,9(5):633-643.
|
[41] |
McDonnell DP,Park S,Goulet MT,et al.Obesity,cholesterol metabolism,and breast cancer pathogenesis[J].Cancer Res,2014,74(18):4976-4982.
|