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Therapeutic effect of expanded wound grafting combined with closed negative pressure drainage on refractory burn infected wounds |
NI shaojun1 XU qiuyue2 |
1. Department of Burn Plastic Hand Surgery, the Fifth Affiliated (Zhuhai) Hospital of Zunyi Medical University, Guangdong Province, Zhuhai 519100, China; 2. Operating Room, the Fifth Affiliated (Zhuhai) Hospital of Zunyi Medical University, Guangdong Province, Zhuhai 519100, China |
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Abstract Objective To investigate the therapeutic effect of expanded wound grafting combined with closed negative pressure drainage (VSD) on refractory burn infected wounds. Methods A total of 76 patients with large area burn infection refractory wounds admitted to the Fifth Affiliated (Zhuhai) Hospital of Zunyi Medical University from June 2020 to June 2021 were selected as the research subjects. They were divided into experimental group and reference group by lottery, with 38 patients in each group. The reference group was treated with expanded skin grafting, and the experimental group was treated with expanded skin grafting combined with VSD. The survival rate of grafted skin, wound healing rate, wound healing days and pain degree of dressing change were compared between the two groups, and the incidence of adverse reactions was recorded. Results The graft survival rate and wound healing rate in the experimental group were higher than those in the reference group, and the differences were statistically significant (P<0.05). The wound healing days of the experimental group were shorter than those of the reference group, and the pain degree score of dressing change was lower than that of the reference group, and the differences were statistically significant (P<0.05).The total incidence of adverse reactions in experimental group was lower than that in reference group, and the difference was statistically significant (P<0.05). Conclusion Expanded skin grafting combined with VSD can promote wound healing, improve the survival rate of skin grafting, and reduce the pain of complications and late dressing change.
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