雷公藤多苷片治疗干燥综合征的临床效果

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Abstract Objective To explore the clinical effect of Tripterygium Glycoside Tablets in the treatment of Sjogren′s syndrome.Methods From January 2020 to May 2021,60 patients with Sjogren′s syndrome admitted to the First Affiliated Hospital of Gannan Medical College were selected as the research objects,and they were divided into the control group (30 cases) and the observation group (30 cases) according to the random number table method.The control group was treated with Prednisone+Hydroxychloroquine Sulfate,and the observation group was treated with Tripterygium Glycoside Tablets.The clinical efficacy,the levels of immunoglobulin,rheumatoid factor,improvement of clinical symptoms,and the incidence of adverse reactions between the two groups were compared.Results The clinical efficacy of the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).After treatment,the levels of IgG and rheumatoid factor (RF) in the observation group were lower than those in the control group,and the differences were statistically significant (P＜0.05).The saliva flow rate and tear flow rate of the observation group were higher than those of the control group,and the numerical evaluation scale (NRS) score of the observation group was lower than that of the control group,the differences were statistically significant (P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion Tripterygium Glycoside Tablets are effective in treating Sjogren′s syndrome.They can effectively improve the symptoms of dry mouth,dry eyes,and joint pain,as well as immune function and rheumatoid factor levels.

Key words： Tripterygium Glycoside Tablets Sjogren&prime s syndrome Curative effect IgG Rheumatoid factor

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	Articles by authors
	JU Yanjuan
	LI Rongping
	ZHOU Shenghui
	HU Jin
	GUO Dibin

Cite this article:

JU Yanjuan,LI Rongping,ZHOU Shenghui, et al. Clinical effect of Tripterygium Glycoside Tablets in treating Sjogren′s syndrome[J]. 中国当代医药, 2022, 29(3): 37-39.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I3/37

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