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| Application effect of Yangzheng Mixture in patients with related anorexia in advanced non-small cell lung cancer |
| SHI Shaoqing HOU Boqun BAO Wenbin |
| The Fifth Department of Oncology, Jiamusi Cancer Hospital |
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Abstract Objective To explore the effect of Yangzheng Mixture in assisting patients with advanced non-small cell lung cancer-related anorexia. Methods From August 2019 to August 2020, 40 patients with non-small cell lung cancer who underwent radiotherapy at the Fifth Department of Oncology, Jiamusi Cancer Hospital, Heilongjiang Province were selected as the subjects of this study. According to the random number table method, they were divided into observation group and control group, with 20 cases in both groups. Patients in the control group were given oral Megestrol Acetate Tablets for treatment, and patients in the treatment group were given Yangzheng Mixture on the basis of the control group. After 3 weeks of treatment, the treatment effects of anorexia symptoms, the Karnofsky functional status score(KPS), the improvement of appetite and the incidence of adverse reactions were compared between the two groups of patients. Results After treatment, the total effective rate of appetite improvement in the treatment group was higher than that in the control group, with statistical significance (P＜0.05); after treatment, the appetite improvement rate in the treatment group was higher than that in the control group, with statistical significance (P＜0.05); after treatment, the total improvement rate of KPS score in the treatment group was higher than that of the control group, with statistical significance (P＜0.05); after treatment, the total adverse reaction rate of patients in the treatment group (35%) was lower than that of the control group (70%), with statistical significance (P＜0.05). Conclusion Yangzheng Mixture can effectively alleviate the related anorexia symptoms caused by radiotherapy in patients with non-small cell advanced lung cancer, improve the patient′s quality of life, and the drug has good clinical efficacy and safety, which is worthy of clinical reference and application.
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