多学科团队在结直肠癌肝转移诊治中的临床应用

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To analyze and study the clinical application effect of multidisciplinary management (MDT) in the treatment of colorectal liver metastasis (CLMs).Methods A total of 42 patients with CLMs who treated in the First People′s Hospital of Huizhou City,Guangdong Province from January 2014 to April 2017 were selected as the research objects and divided into the control group and the observation group by random number table method,with 21 cases in each group.The control group was not achieved MDT,while the observation group was carried out multidisciplinary teamwork for diagnosis and treatment.The preoperative chemotherapy rate,chemotherapy completion conversion rate,surgical conditions and mortality rates of the two groups were compared.Results The preoperative chemotherapy rate and chemotherapy completion conversion rate of the observation group (95.23%,80.95%) were higher than those of the control group (58.33%,53.33%),and the differences were statistically significant (P＜0.05).The proportion of primary resection or ablation in the observation group (76.92%) was higher than that of the control group (27.58%),and the difference was statistically significant (P ＜0.05).The surgical resection rate of metastases in the observation group(75.00%) was higher than that in the control group (33.33%),and the difference was statistically significant (P＜0.05).There were no statistically significant differences in R0 resection rate,lymph node dissection rate,metastasis dissection rate and pathological complete remission rate between the two groups (P＞0.05).The 1-year follow-up mortality rate of the observation group and the control group were 4.76% (1/21) and 9.52% (2/21).There was no statistically significant difference in the 1-year follow-up mortality rate between the two groups (P＞0.05).The 2-year follow-up mortality rate of the observation group and the control group were 38.09% (8/21) and 61.90% (13/21).The 2-year follow-up mortality rate of the observation group was lower than that of the control group,and the difference was statistically significant (P＜0.05).Conclusion The MDT model of multiple methods for sequential treatment of CLMs obtains a definite effect,which is conducive to standarde patient′s preoperative examination and intraoperative chemotherapy,and has a remarkable effect on improving the resection and ablation rate and the resection rate of metastases.It is worthy of clinical promotion and application.

Key words： Colorectal cancer Liver metastases Multidisciplinary management model Sequential treatment with multiple methods Preoperative adjuvant chemotherapy Surgical conditions Mortality

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZENG Hui-ming
	XIAO Ling-hui
	XIE Wei

Cite this article:

ZENG Hui-ming,XIAO Ling-hui,XIE Wei. Clinical application of the multidisciplinary team in the diagnosis and treatment of colorectal liver metastasis[J]. 中国当代医药, 2020, 27(34): 105-107转117.

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2020/V27/I34/105

[1]	李嘉俊，赵杰，赫兰晔，等.结直肠癌肝转移的治疗现状[J].结直肠肛门外科，2017，23（6）：802-806.
[2]	黄理哲.多学科协作诊疗模式在结直肠癌精准个体化治疗中的应用效果[J].广西医学，2018，40（4）：396-398，401.
[3]	疏诚晨，潘旭静，陆春苗.多学科团队协作照护模式在腹腔镜直肠癌手术中的应用[J].蚌埠医学院学报，2019，44（10）：1433-1435.
[4]	周建凤，周炜洵，高鑫，等.多学科诊治可切除性结直肠癌肝转移一例报道[J].中华结直肠疾病电子杂志，2019，8（3）：295-297.
[5]	宋锦添，陈奕贵，杨建伟，等.62例结直肠癌肝转移患者术后复发时间的风险因素[J].临床与病理杂志，2018，38（8）：1646-1650.
[6]	张旭晖，宗源，鲁智豪，等.1例异时性直肠癌肝转移患者的MDT治疗[J].肿瘤综合治疗电子杂志，2019，5（3）：29-31.
[7]	王金，尚培中，张金江，等.结肠癌同时性肝转移骨转移一例多学科团队诊治报道[J].中华普外科手术学杂志（电子版），2019，13（5）：537-539.
[8]	肖乾，任华，沈俐，等.多学科团队诊治直肠癌伴腹股沟淋巴结转移一例[J].中华结直肠疾病电子杂志，2019，8（5）：525-532.
[9]	本刊编辑部.《中国肿瘤临床》文章推荐：结直肠癌肺转移多学科综合治疗专家共识（2018版）[J].中国肿瘤临床，2019，46（14）：744.
[10]	中国医师协会外科医师分会多学科综合治疗专业委员会，中国抗癌协会大肠癌专业委员会.结直肠癌肺转移多学科综合治疗专家共识（2018版）[J].中国肿瘤临床，2019，46（2）：51-63.
[11]	陈真，姚品芳，刘媛媛，等.肿瘤样本库建设与单病种MDT科研模式应用探讨[J].中国肿瘤，2019，28（12）：918-921.
[12]	胡涵光，宋永茂，孙立峰，等.结直肠癌多学科综合诊疗经验分享[J].中华胃肠外科杂志，2019，22（4）：398-400.
[13]	郑晓林，林慧华，张龙，等.MDT模式下药师参与门诊癌痛患者阿片类药物治疗管理的作用研究[J].中国药房，2020，31（6）：750-754.
[14]	米伟阳，史航宇，李楠，等.MDT 结合FSPR 治疗痉挛型脑性瘫痪的临床研究[J].中国妇幼保健，2019，34（24）：5685-5688.
[15]	邵红亮，马君，牟一平.以微创为核心的胰腺恶性肿瘤MDT 新模式的临床应用[J].浙江医学，2019，41（22）：2424-2426.