不同时机冻融胚胎移植妊娠结局比较

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Abstract Objective To compare the pregnancy outcomes of frozen-thawed embryo transfer at different times after oocyte retrieval, and to explore the earliest transplanting time for frozen-thawed embryo transfer. Methods Retrospective analysis of patients who received in vitro fertilization embryo transfer (IVF-ET) at the Reproductive Medicine Center of Women Health Center of Shanxi from January 1 to June 30, 2018 was conducted. Patients who met the inclusion/exclusion criteria of this study were divided into two groups according to the timing of frozen-thawed embryo transfer(FET), with 75 patients in group A who were given FET at the first menstrual cycle after oocyte retrieval, and 165 patients in group B who were given FET after ovaries recovered to the level before superovulation. Ovarian hyperstimulation syndrome (OHSS) classification, endometrial preparation and pregnancy outcomes were compared between the two groups. Results There was no significant difference in OHSS classification between the two groups after oocyte retrieval(P＞0.05). The days of using Estradiol Tablets in group A was shorter than that in group B, and the dosage of Estradiol Tablets was less than that in group B, the differences were statistically significant (P＜0.01). The ovarian volume in group A was larger than that in group B on the day of transplantation, with statistically significant difference (P＜0.01).There were no significant differences in the clinical pregnancy rate, embryo implantation rate, twin rate, early miscarriage rate, late miscarriage rate, premature birth rate and delivery rate between the two groups (P＞0.05). Conclusion FET at the first menstrual cycle after oocyte retrieval does not affect the pregnancy outcomes of patients whose OHSS classification after oocyte retrieval is none, mild and moderate.

Key words： Frozen-thawed embryo transfer Pregnancy rate Delivery rate Ovarian hyperstimulation syndrome

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	Articles by authors
	LIANG Li-xia
	LIU Jun-fen
	FAN Jun-mei
	ZHANG Zhi-ping
	ZHANG Xiu-ping

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LIANG Li-xia,LIU Jun-fen,FAN Jun-mei, et al. Comparison of pregnancy outcomes of frozen-thawed embryo transfer at different timings[J]. 中国当代医药, 2020, 27(28): 8-12.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2020/V27/I28/8

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