Abstract：Objective To evaluate the effect of Ticagrelor on acute ST-elevation myocardial infraction.Methods 120 patients with STEMI admitted to our hospital from January 2016 to January 2017 were performed primary PCI.According to the difference of treatment methods,the patients were divided into Ticagrelor group and Clopidogrel group.At the third month after procedure,the incidence of bleeding and major adverse cardiovascular events(MACE)between two groups were compared.Results In Ticagrelor group,the incidence of MACE was 3.3%,which was lower than that in the Clopidogrel group(8.3%),but no significant difference was observed between both groups(P＞0.05).Additionally,the incidence of bleeding,major without,minor was no significant difference was found between both groups(P＞0.05).Conclusion Ticagrelor has a tendency to reduce the incidence of MACE,without the increase of the bleeding incidence,in elderly patients with STEMI.
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