Abstract：ObjectiveTo observe the influence of Sufentanil and Fentanyl used for anaesthesia on hemodynamics in elderly patients with laparoscopic cholecystectomy.Methods156 elderly patients with gradeⅠ-Ⅱ of ASA and scheduled for laparoscopic cholecystectomy in our hospital from April 2016 to August 2017 were selected as object and they were randomly divided into the Sufentanil group and Fentanyl group according to the random number table method,and there were 78 cases in each group.The Fentanyl group was combined with Fentanyl for anesthesia induction and maintenance,and Sufentanil was used in the Sufentanil group.The change of HR,SBP and DBP before anesthesia induction(T0),after induction(T1),intubation(T2)and after extubation(T3)in patients between the two groups were compared.At the same time,the revival situation and the incidence of adverse reactions in patients between the two groups were compared.ResultsHR,SBP and DBP at T1were significantly lower than those at T0in the two groups,and the abovementioned-indexes at T2and T3were significantly higher than those at T0(P＜0.05).HR,SBP and DBP at T1in the Sufentanil were significantly higher than those in the Fentanyl group,and HR,SBP and DBP at T2,T3in the Sufentanil were significantly lower than those in the Fentanyl group (P＜0.05).Time required for anaesthesia recovery,spontaneous breathing recovery and extubation in patients of the Sufentanil group were significantly shorter than those of the Fentanyl group (P＜0.01).The total incidence of respiratory depression,gastrointestinal reaction,irritability and arrhythmia and so on in the Sufentanil group was significantly lower than that of the Fentanyl group (P＜0.05).ConclusionIn the induction and maintenance of anesthesia for elderly patients with laparoscopic cholecystectomy,Fentanyl and Sufentanil can influence the hemodynamics of patients,but compared with Fentanyl,Sufentanil in maintaining the hemodynamic stability has a more prominent role,at the same time,it can also promote the recovery of patients after anesthesia with fewer adverse reactions,it is worthy of clinical promotion and application.
刘荣伟. 舒芬太尼与芬太尼麻醉对老年腹腔镜胆囊切除术患者血流动力学的影响[J]. 中国当代医药, 2018, 25(3): 67-69转72.
LIU Rong-wei. Influence of Sufentanil and Fentanyl used for anaesthesia on hemodynamics in elderly patients with laparoscopic cholecystectomy. 中国当代医药, 2018, 25(3): 67-69转72.