ObjectiveEvaluation of clinical effect of Misoprostol on different routes of medication in the treatment of missed abortion.Methods80 cases of patients with missed abortion from putian college affiliated hospital from January 2015 to June 2016 were selected as the subjects,and randomly divided into the experimental group and the control group,40 cases in each group.The test group received150 mg oral Mifepristone combined with Misoprostol 0.6 mg plug vagina.The control group received 150 mg oral Mifepristone combined with Misoprostol 0.6 mg oral.The uterine contraction time,time of discharge of embryo after taking medicine,the amount of bleeding and the rate of complete abortion after 2 hours between the two groups were observed and compared.ResultsIn the experimental group,the time of uterine contraction and the discharge time were significantly less than those in the control group,the difference was statistically significant(P<0.05).The amount of bleeding in the experimental group was significiantly less than that in the control group after 2 h,the difference was statistically significant(P<0.05).The complete abortion rate was 20.0%in the test group,higher than 5.0%in the control group,the difference was statistically significant(P<0.05).ConclusionMifepristone combined Misoprostol plug vagina for missed abortion has better clinical efficacy than Mifepristone combined Misoprostol oral,which has the lower rate of embryos after discharge.