营养炎症指标在脓毒症中的研究进展

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摘要

脓毒症是一种宿主感染有害反应而导致的器官功能障碍，严重可危及患者的生命。脓毒症作为一种困扰人类健康数十年的疾病，迄今为止还没有具体的诊断或治疗指标。在过去的10 年中，不断开展的研究提高了人们对脓毒症的认识，增加了临床医生对该疾病的理解，并改善了脓毒症的临床预后。脓毒症与重症监护室的高死亡率有关，并伴有全身炎症反应、继发感染和多器官衰竭等。脓毒症是儿科重症监护室患者死亡的主要原因之一，及时和适当的治疗可以提高儿童脓毒症患者的预后。对脓毒症的早期诊断和病情评估至关重要。营养炎症指标在脓毒症早期诊断和预测中发挥着重要作用。因此，本文就营养炎症指标在脓毒症中的研究进展展开综述，以期为脓毒症的诊治提供理论依据。

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关键词 ：脓毒症, 营养炎症指标, 早期诊断, 病情评估

Abstract：

Sepsis is an organ dysfunction caused by a harmful response to host infection,which can seriously endanger the patient's life.Sepsis,as a disease that has plagued human health for decades,has yet to have specific diagnostic or therapeutic indicators.Over the past 10 years,continuous research has increased people's understanding of sepsis,increased clinical doctors'understanding of the disease,and improved the clinical prognosis of sepsis.Sepsis is associated with high mortality rates in intensive care units,accompanied by systemic inflammatory reactions,secondary infections,and multiple organ failure.Sepsis is one of the main causes of death in pediatric intensive care units,and timely and appropriate treatment can improve the prognosis of pediatric sepsis patients.Early diagnosis and assessment of sepsis are crucial.Nutritional inflammatory markers play an important role in the early diagnosis and prediction of sepsis.Therefore,this article reviews the research progress of nutritional inflammation indicators in sepsis,in order to provide theoretical basis for the diagnosis and treatment of sepsis.

Key words： Sepsis Nutritional inflammation indicators Early diagnosis Disease assessment

基金资助: 江苏省第五期“333 工程”科研资助计划项目（BRA2020227）；
江苏省卫生健康委科研项目（LGY2019044）；
淮安市自然科学研究计划（联合专项）卫生健康类科研项目（HABL202251）。

引用本文:

苗业权；刘成全；颜猛；林小飞；朱红利. 营养炎症指标在脓毒症中的研究进展[J]. 中国当代医药, 2024, 31(16): 178-183.
MIAO Yequan LIU Chengquan YAN Meng LIN Xiaofei▲ ZHU Hongli. Research progress on nutritional inflammation indicators in sepsis. 中国当代医药, 2024, 31(16): 178-183.

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https://www.dangdaiyiyao.com/CN/ 或 https://www.dangdaiyiyao.com/CN/Y2024/V31/I16/178

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