慢性肾脏病非透析患者药物依从性现状及影响因素分析

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摘要目的调查慢性肾脏病（CKD）非透析患者的药物依从性的现状，并分析其影响因素。方法采用便利抽样法选取2022 年10 月至2023 年5 月南华大学附属第一医院肾内科收治的220例CKD 非透析患者作为调查对象，收集患者的一般资料、药物依从性、合理用药的自我效能、服药信念等相关量表评分，并进行患者药物依从性的相关因素分析。结果共纳入220例CKD 非透析患者，患者的Morisky-8 药物依从性量表得分为（2.96±1.20）分，处于较低水平。单因素分析结果显示，患者的性别、文化程度、职业状况、付费方式与药物依从性有关，差异有统计学意义（P＜0.05）。采用多元线性回归模型进行多因素分析结果显示，患者的职业、付费方式、用药自我效能、服药一般信念是患者药物依从性的影响因素（P＜0.05）。此外药物依从性与用药自我效能呈一定程度的正相关（r=0.558），与服药一般信念呈一定程度的负相关（r=-0.510）。结论 CKD 非透析患者用药依从性较差，建议医护人员采取相应的护理措施，提高患者的用药自我效能及药物依从性。

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关键词 ：慢性肾脏病, 药物依从性, 自我效能, 服药信念, 影响因素

Abstract：Objective To investigate the current situation of medication compliance in non-dialysis patients with chronic kidney disease (CKD)and analyze its influencing factors.Methods A total of 220 non-dialysis patients with CKD admitted to the Department of Renal Medicine of the First Affiliated Hospital of University of South China from October 2022 to May 2023 were selected by convenience sampling method.The general data,medication compliance,self-efficacy of rational drug use,medication belief and other relevant scales of patients were collected.The factors related to medication compliance were analyzed.Results A total of 220 non-dialysis patients with CKD were included.The score of Morisky-8 medication compliance scale was (2.96±1.20)points,which was at a low level.The results of univariate analysis showed that gender,education level,occupational status and payment method of patients were related to medication compliance,and the differences were statistically significant (P＜0.05).Multivariate linear regression model was used to analyze the factors,and the results showed that patients' occupation,payment method,drug self-efficacy and general medication belief were the influencing factors of patients'drug compliance(P＜0.05).In addition,medication compliance was positively correlated with drug self-efficacy to a certain extent (r=0.558),and general medication belief was negatively correlated to a certain extent(r=-0.510).Conclusion The medication compliance of non-dialysis patients with CKD is poor.It is suggested that the medical staff should take corresponding nursing measures to improve the medication self-efficacy and medication compliance of patients.

Key words： Chronic kidney disease Medication compliance Self-efficacy Medication belief Influencing factor

通讯作者: 万艳平（1965-），女，湖南衡阳人，硕士，教授，硕士研究生导师，主要从事高等护理教育工作。

作者简介: 彭颖倩（1990-），女，湖南衡阳人，南华大学2021级护理学专业在读硕士研究生，主要从事肾病护理工作。

引用本文:

彭颖倩；万艳平. 慢性肾脏病非透析患者药物依从性现状及影响因素分析[J]. 中国当代医药, 2024, 31(13): 101-105.
PENG Yingqian WAN Yanping. Analysis of current situation and influencing factors of medication compliance in non-dialysis patients with chronic kidney disease. 中国当代医药, 2024, 31(13): 101-105.

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https://www.dangdaiyiyao.com/CN/ 或 https://www.dangdaiyiyao.com/CN/Y2024/V31/I13/101

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