Abstract：Objective To explore the factors influencing suicidal behaviors in patients with depression.Methods A total of 125 patients with depression who had not been treated by the drug system in Shandong Daizhuang Hospital from October 2021 to December 2022 were retrospectively selected as the study objects,and divided into depression suicidal behavior group(55 cases)and depression without suicidal behavior group(70 cases)according to whether they were accompanied by suicidal behavior.Blood platelet count,platelet distribution width,mean platelet volume and platelet pressure were measured by blood analyzer to analyze the influencing factors of depression accompanied by suicidal behavior.Results There were statistically significant differences in platelet count,mean platelet volume and platelet distribution width between the two groups (P＜0.05).The results of multivariate analysis suggested that mean platelet volume (β=-0.48,OR=0.62,95%CI=0.39-0.98)was a protective factor affecting the occurrence of suicidal behavior in depression (P＜0.05).Conclusion The mean platelet volume is closely related to the occurrence of suicidal behaviors in depression.This finding could provide a potential biomarker for the clinical prediction of suicide risk in patients with depression.
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