稳心颗粒对气阴两虚型慢性心力衰竭患者心功能及疲乏状况的影响

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摘要目的探讨稳心颗粒治疗气阴两虚型慢性心力衰竭的效果。方法选取2021 年1 月至2022 年12 月岳阳市人民医院收治的120 例慢性心力衰竭（气阴两虚型）患者作为研究对象，按照随机数字表法将其分为对照组与研究组，每组60 例。对照组采用常规药物治疗，研究组在此基础上采用稳心颗粒治疗。比较两组患者临床效果及不良反应、多维疲劳量表评分、左心室射血分数、左室舒张末期内径、左室收缩末期内径。结果研究组患者总有效率高于对照组，差异有统计学意义（P＜0.05）。两组患者均未发生严重不良反应。两组患者治疗后多维疲劳量表评分、左室舒张末期内径、左室收缩末期内径水平低于本组治疗前，且研究组患者上述指标低于对照组，差异有统计学意义（P＜0.05）；两组患者治疗后左心室射血分数高于本组治疗前，且研究组患者左心室射血分数高于对照组，差异有统计学意义（P＜0.05）。结论稳心颗粒治疗气阴两虚型慢性心力衰竭的效果及安全性均较高，可有效减轻疲乏状况及提高心功能。

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关键词 ：稳心颗粒, 气阴两虚型, 慢性心力衰竭, 心功能, 疲乏状况

Abstract：

Objective To investigate the effect of Wenxin Granules on qi-yin deficiency type chronic heart failure.Methods A total of 120 patients with chronic heart failure (qi-yin deficiency type) admitted to Yueyang People's Hospital from January 2021 to December 2022 were selected as the research objects,and they were divided into control group and study group according to random number table method,with 60 cases in each group.The control group was treated with conventional drugs,and the study group was treated with Wenxin Granules on this basis.The clinical effect and adverse reactions,multidimensional fatigue scale score,left ventricular ejection fraction,left ventricular end-diastolic diameter and left ventricular end-systolic diameter were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group,the difference was statistically significant (P＜0.05).No serious adverse reactions occurred in both groups.After treatment,the scores of multidimensional fatigue scale,left ventricular end-diastolic diameter and left ventricular end-systolic diameter of the two groups were lower than those before treatment,and the above indexes of the study group were lower than those of the control group,with statistical significances(P＜0.05).The left ventricular ejection fraction of the two groups were higher after treatment than those before treatment,and the left ventricular ejection fraction of the study group was higher than that of the control group,with statistical significances(P＜0.05).Conclusion Wenxin Granules has high efficacy and safety in treating qi-yin deficiency type chronic heart failure,which can effectively reduce fatigue and improve heart function.

Key words： Wenxin Granules Qi-yin deficiency type Chronic heart failure Heart function Fatigue condition

引用本文:

朱方; 田玥;彭高伟;李燕. 稳心颗粒对气阴两虚型慢性心力衰竭患者心功能及疲乏状况的影响[J]. 中国当代医药, 2024, 31(18): 107-110.
ZHU Fang1 TIAN Yue2 PENG Gaowei2 LI Yan1▲. Effect of Wenxin Granules on heart function and fatigue in patients with qi-yin deficiency type chronic heart failure. 中国当代医药, 2024, 31(18): 107-110.

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https://www.dangdaiyiyao.com/CN/ 或 https://www.dangdaiyiyao.com/CN/Y2024/V31/I18/107

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