Clinical efficacy of repetitive transcranial magnetic stimulation in patients with dysphagia in stroke
YANG Huajun ZHANG Yingzheng HU Saiqin ZHENG Yingtao LIN Xiang YIN Lufeng
The First Department of Rehabilitation Medicine,the Third People's Hospital,Fujian University of Traditional Chinese Medicine,Fujian Province,Fuzhou 350100,China
Abstract：Objective To explore the clinical therapeutic effects of repetitive transcranial magnetic stimulation (rTMS) on normal and affected cerebral hemispheres of patients with dysphagia after stroke.Methods A total of sixty patients with dysphagia after stroke who were admitted to the Third People's Hospital Affiliated to Fujian University of Chinese Medicine from October 2019 to October 2022 were selected as the study objects.According to random number table method,they were divided into control group(20 cases),trial group A(20 cases)and trial group B(20 cases).The control group received conventional dysphagia treatment,and 5 Hz rTMS was applied to the affected or unaffected area on the basis of conventional treatment in the test A and test B groups,respectively,and both intervened for 3 weeks.The clinical swallowing function and inflammatory factor changes in each group before and after the intervention were assessed by measuring serum inflammatory factors and using the fiberoptic endoscopic dysphagia severity scale(FEDSS),the penetration aspiration scale(PAS),and the standardized swallowing assessment(SSA).Results After intervention,FEDSS,PAS and SSA scores of trial group A and trial group B were lower than those of control group,with statistical significance(P＜0.05).There was no significant difference in FEDSS,PAS and SSA scores between trial group A and trial group B(P＞0.05).The levels of interferon-γ,tumor necrosis factor-α and interleukin 6 in trial group A were lower than those in trial group B and control group,and the difference was statistically significant(P＜0.05),while only interferon-γ in trial group B was lower than that in control group,and the difference was statistically significant(P＜0.05).Conclusion 5 Hz high-frequency rTMS stimulation of normal and affected hemispheres has positive effects on post-stroke dysphagia patients,but stimulation of the affected area is more advantageous for improving the expression of inflammatory factors in patients.
杨华军； 张颖铮； 胡赛琴； 郑樱桃； 林湘； 尹鹭峰. 重复经颅磁刺激对脑卒中吞咽障碍患者的临床疗效观察[J]. 中国当代医药, 2024, 31(17): 46-50.
YANG Huajun ZHANG Yingzheng HU Saiqin ZHENG Yingtao LIN Xiang YIN Lufeng. Clinical efficacy of repetitive transcranial magnetic stimulation in patients with dysphagia in stroke. 中国当代医药, 2024, 31(17): 46-50.
京公网安备 11010502046607号