Objective To investigate the effect of intravenous controlled labor analgesia with Remifentanil on labor process and maternal and infant outcomes.Methods A total of 120 cases of parturient who underwent painless labor in Quanzhou Women's and Children's Hospital from September 2021 to March 2022 were selected as the research objects.According to the random number table method,they were divided into observation group and control group,with 60 cases in each group.The control group used epidural analgesia,and the observation group used Remifentanil intravenous controlled labor analgesia.The labor process and maternal and infant outcomes were compared between the two groups.Results The first stage of labor process,the second stage of labor process,the third stage of labor process and the total stage of labor process in the observation group were shorter than those in the control group,the differences were statistically significant (P＜0.05).The total incidence of adverse maternal and infant outcomes in the observation group was lower than that in the control group,the difference was statistically significant (P ＜0.05).Conclusion Intravenous controlled labor analgesia with Remifentanil can shorten the labor process and reduce the incidence of adverse maternal and infant outcomes.