Abstract:Objective To investigate the influencing factors of left ventricular thrombosis (LVT) in patients with acute anterior wall myocardial infarction.Methods Clinical data of 132 patients with acute anterior wall myocardial infarction confirmed in Yuebei People's Hospital from April 2017 to April 2021 were retrospectively analyzed.They were divided into the thrombus group (n=46) and the non-thrombus group (n=86) according to the occurrence of LVT.Logistic regression was used to analyze the factors affecting LVT formation,and ROC curve was used to analyze the value of neutrophil lymphocyte ratio (NLR) in predicting LVT.Results Univariate analysis showed that the increase of ventricular aneurysm ratio,White blood cells (WBC),neutrophil count (NEU),NLR,platelet lymphocyte ratio (PLR),monocyte lymphocyte ratio (MLR),percutaneous coronary intervention (PCI),left ventricular ejection fraction (LVEF),lymphocyte count (LYM) and albumin (ALB) were related to the formation of LVT after acute anterior wall myocardial infarction,There was significant difference (P<0.05).Multivariate logistic regression analysis showed that the formation of ventricular aneurysm (β=2.028,OR=7.602,95%CI =2.003-28.857),Alb decreased (β=0.152,OR=1.165,95%CI =1.015-1.337) was an independent risk factor for LVT after acute anterior wall myocardial infarction (P<0.05).ROC curve showed that the optimal cut-off point of NLR for predicting left ventricular thrombosis after acute anterior wall myocardial infarction was 8.071,the area under ROC curve was 0.751,and its sensitivity was 0.587 and specificity was 0.837.Conclusions The formation of ventricular aneurysm and decreased albumin level were independent risk factors for LVT in acute anterior wall myocardial infarction.NLR is related to the occurrence of LVT,and the risk of LVT increases with the increase of NLR level.