Abstract：Objective To investigate the application effect on the intensive insulin intervention on critically ill patients in Emergency ICU.Methods A total of 60 ICU critically ill patients with stress hyperglycemia admitted to ShangRao People's Hospital from January to December 2021 were selected as research objects.They were randomly divided into routine treatment group (target blood sugar controlled at 6.1-8.1 mmol/L) and intensive treatment group (target blood sugar controlled at 4.1-6.1 mmol/L),with 30 patients in each group.The routine treatment group was treated with conventional insulin treatment intervention,and the intensive treatment group was treated with insulin intensive therapy.The disease indicators,blood glucose management effect before and after treatment and prognosis were compared between the two groups.Results The ICU stay time,electrocardiogram monitoring time,insulin pumping time and discharge time in intensive treatment group were shorter than those in conventional treatment group,with statistically significant differences (P＜0.05).After treatment,the fasting plasma glucos (FPG) level of the two groups was lower than that before treatment,and the insulin sensitivity index (ISI) and insulin resistance index (HOMA-IR) levels were higher than those before treatment,with statistically significant differences (P＜0.05).After treatment,the FPG level in intensive treatment group was lower than that in conventional treatment group,and the ISI and HOMA-IR levels in intensive treatment group were higher than those in conventional treatment group,with statistically significant differences(P＜0.05).There was no statistically significant difference in the total incidence of poor prognosis such as hypoglycemia,dyspnea,nosocomial infection and death between the two groups (P＞0.05).Conclusion Intensive insulin intervention can improve stress hyperglycemia and prognosis of critically ill patients in ICU.
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