Abstract: Objective To explore the clinical effect of seamless rapid cooling pre-hospital and in-hospital for the treatment of thermoplegia.Methods The clinical data of 45 patients with thermoplegia treated from July 2015 to November 2019 in Nanchang Third Hospital were retrospectively analyzed.According to different time points of starting rapid cooling,they were divided into observation group (n=24) and control group (n=21).After admission,patients in the control group received rapid cooling and multi-organ function support treatment;in the observation group,patients were provided with rapid cooling by the pre-hospital emergency staff and received the same treatment as the control group after admission.The time required the anal temperature to fall to 37°C,hospital stay,and the levels of creatinine (Cre),creatine kinase (CK),alanine aminotransferase (ALT) and prothrombin time (PT) were compared between the two groups.Results The time required for the anal temperature of the observation group to fall to 37℃,hospital stay,and PT were shorter than those of the control group,and the levels of Cre,CK,and ALT were lower than those of the control group,the differences were statistically significant (P<0.05).Conclusion By initiating a standardized pre-hospital emergency force,implementing rapid cooling for patients with thermoplegia as soon as possible can reduce the degree of organ damage and is conducive to improving the prognosis of patients.
熊 涛 金 燕 许文鹏. 院前院内无缝式快速降温治疗热射病的临床研究[J]. 中国当代医药, 2020, 27(32): 56-58.
XIONG Tao JIN Yan XU Wen-peng. Clinical study of seamless rapid cooling pre-hospital and in-hospital for the treatment of thermoplegia. 中国当代医药, 2020, 27(32): 56-58.
Harlan SL,Chowell G,Yang S,et al.Heat-related deaths in hot cities:estimates of human tolerance to high temperature thresholds[J].Int J Environ Res Public Health,2014,11(3):3304-3326.
Miller KC,Hughes LE,Long BC,et al.Validity of core temperature measurements at 3 rectal depths during rest,exercise,cold-water immersion,and recovery[J].J Athl Train,2017,52(4):332-338.
[9]
Epstein Y,Roberts WO,Golan R,et al.Sepsis,septic shock,and fatal exertional heat stroke[J].Curr Sport Med Rep,2015,14(1):64-69.
Casa DJ,McDermott BP,Lee EC,et al.Cold Water Immersion:The gold standard for exertional heatstroke treatment cold water immersion:The gold standard for exertional heatstroke treatment[J].Exerc Sport Sci Rev,2007,35(3):141-149
Bai L,Ding G,Gu S,et al.The effects of summer temperature and heat waves on heat-related illness in a coastal city of Chi,2011-2013[J].Environ Res,2014,13(2):212-219.
[14]
Alzeer AH,Wissler EH.Theoretical analysis of evaporative cooling of classic heat stroke patients[J].Int J Biometeorol,2018,62(9):1567-1574.
[15]
Casa DJ,Armstrong LE,Ganio MS,et al.Exertional heat stroke in competitive athletes[J].Curr Sports Med Rep,2005,4(6):309-317.
[16]
Gaudio FG,Grissom CK.Cooling methods in heat stroke[J].J Emerg Med,2015,50(4):607-616.