Abstract： Objective To analyze adverse drug reactions in Pizhou People′s Hospital (hereinafter referred to as "our hospital") in 2018.Methods A total of 318 adverse drug reaction reports from January to December 2018 of our hospital were analyzed.The general situation，severity of adverse reactions，patient′s primary diseases，previous adverse drug history，family adverse drug history，types of adverse drugs，dosage forms，routes of administration，main manifestations and results of adverse reactions were analyzed.Results Altogether 188 were males (59.12%) and 130 were females(40.88%);the highest proportion was ＞40-60 years old，accounting for 35.85%.Respiratory diseases accounted for 25.79% of the patient′s primary diseases.The proportions of Chinese patent medicine and antibacterial medicine were higher，accounting for 30.19% and 15.72% respectively.The main dosage forms were oral dosage form and injection powder injection，accounting for 55.56% and 42.14% respectively;in the route of administration，the proportions of oral and intravenous drugs were higher，accounting for 55.35% and 41.82% respectively.The main adverse reactions were gastrointestinal symptoms，allergic reactions and nervous system reactions，accounting for 39.62%，36.16% and 14.15%respectively，among which 4 patients had shock.306 cases improved，accounting for 96.23%，10 cases recovered，accounting for 3.14%.Conclusion From January to December 2018，the ADR patients in our hospital are mainly middleaged and elderly people.The proportion of Chinese patent medicine and antibacterial medicine is relatively high，and the proportion of oral and injection minute injection is relatively high.Most of them are general ADRs，but some patients have severe shock，and most of them have improved or recovered.
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