Abstract： Objective To analyze the changes and significance of biochemical test items in patients with liver cirrhosis.Methods A total of 160 patients with liver cirrhosis who were treated in Liaoyang Infectious Disease Hospital from June 2017 to June 2019 were randomly selected as the observation group.Among them，53 patients were in the early stage (33.13%)，53 patients were in the middle stage (33.13%)，and 54 patients (33.75%) were in the late stage.Then 160 healthy people who came to the hospital for physical examination during the same time period were selected as the control group.The venous blood samples of the two groups were collected and used as biochemical test samples，and then the main biochemical test items were tested with an automatic biochemical analyzer to compare the biochemical test items of the two groups.Results The levels of N-acetyl-β-d glucosaminidase (NAG)，α-fucosidase (AFU)，prealbumin (PAB)，leucine aminopeptidase (LAP)，aspartate amino transfer isoenzyme (ASTm)，glutamate dehydrogenase(GLDH)，adenosine deaminase (ADA) and α-fetoprotein (AFP) in the observation group were higher than those in the control group，and the differences were statistically significant (P＜0.05).The levels of NAG，AFU，PAB，LAP，ASTm，GLDH，ADA，and AFP in the advanced patients were higher than those in the early and middle stage patients，while NAG，AFU，PAB，LAP，ASTM，GLDH，ADA，and AFP levels in the middle stage patients were higher than those in the early stage patients，the differences were statistically significant (P＜0.05).Conclusion The implementation of biochemical test items for diagnosis of patients with liver cirrhosis in the clinic can provide effective reference value for later clinical treatment and promote a significant increase in clinical accuracy.
纪金玲 程晓彤 王 茜 朱天星 杨娇娜. 生化检验项目在肝硬化疾病患者中的变化及意义[J]. 中国当代医药, 2020, 27(33): 164-166.
JI Jin-ling CHENG Xiao-tong WANG Qian ZHU Tian-xing YANG Jiao-na. Changes and significance of biochemical test items in patients with liver cirrhosis. 中国当代医药, 2020, 27(33): 164-166.
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