间苯三酚在宫颈条件不良妊娠引产中的应用效果观察

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摘要目的探讨间苯三酚在宫颈条件不良妊娠引产中的应用效果。方法选取2019年12月～2020年5月联勤保障部队第九〇〇医院莆田医疗区妇产科收治的102例宫颈条件不良妊娠患者作为研究对象，按照随机数字表法分为观察组（51例）与对照组（51例），观察组采用间苯三酚治疗方法，对照组采用山莨菪碱治疗方法，两组最多治疗3 d。比较两组的引产成功率、用药至胎儿娩出时长、产后出血量、新生儿出生后1 min 的Apgar 评分、宫颈成熟度（Bishop）评分及不良反应发生情况。结果观察组引产成功率高于对照组，用药至胎儿娩出时长短于对照组，产后出血量少于对照组，新生儿出生后1 min 的Apgar 评分高于对照组，差异均有统计学意义（P＜0.05）。引产前，两组Bishop 评分比较，差异无统计学意义（P＞0.05）；用药结束后12 h，两组宫颈Bishop 评分均较引产前升高，且观察组高于对照组，差异有统计学意义（P＜0.05）。观察组不良反应发生率低于对照组，差异有统计学意义（P＜0.05）。结论宫颈条件不良妊娠产妇采用间苯三酚引产效果显著，可以提高引产有效率，改善宫颈条件，缩短产程，优化分娩结局，且用药安全性高，值得临床推广。

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	沈木桂陈丽云赖娟娟▲

关键词 ： , font-size: 16px, text-align: justify, 引产')" href="#">">引产, 宫颈条件不良妊娠, 间苯三酚, 妊娠结局

Abstract： Objective To investigate the application effect of Phloroglucinol in the induction of labor in pregnancy with poor cervical conditions.Methods A total of 102 pregnant patients with dysfunctional cervical conditions admitted to the Department of Obstetrics and Gynecology，Putian Medical District，No.900 Hospital of Joint Logistics Support Force from December 2019 to May 2020 were selected as the research objects，and they were divided into the observation group (51 cases) and the control group (51 cases) according to random number table method.The observation group received the Phloroglucinol for treating method，and the control group received the Anisodamine for treating method.Two groups were treated for up to 3 days.The success rate of labor induction，the time from medication to the delivery of the fetus，the amount of postpartum hemorrhage，the Apgar score of the newborn 1 min after birth，the cervical maturity(Bishop) score and adverse reactions of the two groups were compared.Results The success rate of labor induction in the observation group was higher than that in the control group，the time from medication to fetus delivery was shorter than that in the control group，postpartum hemorrhage was less than that in the control group，the Apgar score of the newborn at 1 min after birth was higher than that of the control group，and the differences were statistically significant(P＜0.05).Before labor induction，there was no statistically significant difference of cervical Bishop score between the two groups (P＞0.05);12 h after the end of the medication，the Bishop scores of the two groups were higher than those before labor induction，and the observation group was higher than the control group，the differences were statistically significant (P＜0.05).The incidence of adverse reactions in the observation group was lower than that in the control group，and the difference was statistically significant (P＜0.05).Conclusion The use of Phloroglucinol to induce labor in pregnant women with poor cervical conditions has a significant effect，which can increase the effective rate of labor induction，improve cervical conditions，shorten labor，optimize delivery outcomes，and have high drug safety，which is worthy of clinical promotion.

Key words： font-size: 16px Induction of labor;Pregnancy with poor cervical conditions;Phloroglucinol;Pregnancy outcome')" href="#">text-align: justify;">Induction of labor;Pregnancy with poor cervical conditions;Phloroglucinol;Pregnancy outcome

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通讯作者: 赖娟娟（1969-），女，汉族，福建莆田人，本科，副主任医师，研究方向：妇产科危重症救治

引用本文:

沈木桂陈丽云赖娟娟▲. 间苯三酚在宫颈条件不良妊娠引产中的应用效果观察[J]. 中国当代医药, 2020, 27(33): 115-117.
SHEN Mu-gui CHEN Li-yun LAI Juan-juan▲. Observation on the application effect of Phloroglucinol in the induction of labor in pregnancy with poor cervical conditions. 中国当代医药, 2020, 27(33): 115-117.

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https://www.dangdaiyiyao.com/CN/ 或 https://www.dangdaiyiyao.com/CN/Y2020/V27/I33/115

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