Efficacy of Ethinyl Estradiol Cyproterone Tablets combined with levonorgestrel-releasing intrauterine system in the treatment of ovulatory abnormal uterine bleeding
LUO Chunyan1 XIA Qiao2 CHEN Hong2
1. Department of Obstetrics and Gynecology, Ji′an Central People′s Hospital, Jiangxi Province, Ji′an 343000, China;
2. Department of Obstetrics and Gynecology, People′s Hospital of Yanshan County, Shangrao City, Jiangxi Province,Yanshan 334000, China
Abstract：Objective To investigate the effect of Ethinyl Estradiol Cyproterone Tablets combined with levonorgestrelreleasing intrauterine system (LNG-Ius) in the treatment of ovulatory abnormal uterine bleeding. Methods From January 2019 to January 2021, 160 patients with ovulatory abnormal uterine bleeding who were admitted to the Department of Obstetrics and Gynecology of Ji′an Central People′s Hospital were selected as the research objects, they were divided into the control group (80 cases) and the observation group (80 cases) according to the random number table method.The control group was treated with LNG-Ius, and the observation group was treated with Ethinyl Estradiol Cyproterone Tablets combined with LNG-Ius. The clinical treatment effect, menstrual blood loss score and sex hormone levels were compared between the two groups. Results The total effective rate of clinical treatment in the observation group after treatment was higher than that in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the menstrual blood loss score between the two groups before treatment (P>0.05). The menstrual blood loss score in the observation group after treatment was lower than that in the control group, and the difference was statistically significant (P<0.05). Before treatment, there were no statistical differences in the levels of estradiol (E2), luteinizing hormone (LH) and follicle-stimulating hormone (FSH) between the two groups (P>0.05). After treatment, the E2, LH and FSH levels of the observation group were lower than those of the control group, and the differences were statistically significant (P<0.05). Conclusion For patients with ovulatory abnormal uterine bleeding, the combination of Ethinyl Estradiol Cyproterone Tablets combined with LNG-Ius has a better therapeutic effect, which can effectively improve the level of sex hormones and is conducive to the recovery of the patients′ condition.
罗春艳；夏桥；陈虹. 炔雌醇环丙孕酮片联合左炔诺孕酮宫内释放系统治疗排卵障碍性异常子宫出血的效果[J]. 中国当代医药, 2022, 29(27): 100-103.
LUO Chunyan； XIA Qiao；CHEN Hong. Efficacy of Ethinyl Estradiol Cyproterone Tablets combined with levonorgestrel-releasing intrauterine system in the treatment of ovulatory abnormal uterine bleeding. 中国当代医药, 2022, 29(27): 100-103.
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