Abstract：Objective To study the control effect of different enteral nutrition (EN) preparation on stress hyperglycemia in severe patients in neurosurgical intensive care unit (NICU). Methods From August 2019 to December 2020, 64 severe patients with stress hyperglycemia in NICU, Department of Neurosurgery, the First Affiliated Hospital of Fujian Medical University, were retrospectively selected as the research objects. They were randomly divided into the control group (32 cases) and the observation group (32 cases) according to random number table method. Patients in the control group were treated with whole protein EN preparation (Nutrison Fiber), and patients in the observation group were treated with EN preparation containing slow-release starch (Ruidai EN solution). Patients in the two groups were given constant rate of infusion of the nutrition pump through a nasogastric tube. The levels of glusoes average (GLUave), the glusoes maximumn (GLUmax), the glusoes minimum (GLUmin), the glusoes standard deviation (GLUsd), the glusoes coefficient of variation (GLUcv) and the incidence of hyperglycemia were compared between the two groups. The levels of serum total protein, albumin, triacylglycerol and total cholesterol were recorded before and after treatment between the two groups, and the incidence of feeding intolerance was observed between the two groups. Results The levels of GLUave, GLUmax, GLUsd, GLUcvand the incidence rate of hyperglycemia of the observation group patients were lower than those of the control group, and the level of GLUminof the observation group was higher than that of the control group, the differences were statistical significance (P＜0.05). There were no significant differences in the levels of serum total protein, albumin, triacylglycerol and total cholesterol between the two groups before treatment (P＞0.05). The levels of serum total protein, albumin of the two group after treatment were higher than before treatment, the differences were statistical significance (P＜0.05). There were no significant differences in the levels of triacylglycerol and total cholesterol between the two groups after treatment (P＞0.05). There was no significant difference in the incidence of feeding intolerance between the two groups (P＞0.05). Conclusion Ruidai EN solution can better control the blood glucose level and blood glucose fluctuations of critically ill patients in neurosurgery NICU, and effectively observe and evaluate the feeding tolerance of patients.
连玉枝. 不同肠内营养液对神经外科术后应激性高血糖重症患者的影响[J]. 中国当代医药, 2022, 29(25): 58-61.
LIAN Yuzhi. Influence of different enteral nutrition preparation on severe patients with stress hyperglycemia after neurosurgery. 中国当代医药, 2022, 29(25): 58-61.
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