Analysis of prescription medication law of ancient doctors of Huxiang medical school in the treatment of madness
LI Shu1 SHAN Yanliang
1.Department of Radiology,Xiangya Hospital,Central South University,Hu′nan Province,Changsha 410000,China;
2.Department of Radiology,the First Affiliated Hospital of Hunan University of Chinese Medicine,Hu′nan Province,Changsha 410007,China.
Abstract：Objective Through data mining,the clinical experience and medication characteristics of the ancient doctors of Huxiang medical school on the theory,method,prescription and medicine of insanity were explored.Methods The software SPSS 18.0,SPSS Modeler 18.0 were used for cluster analysis and association analysis,to make a statistical analysis on high-frequency drugs,common drug efficacy,sexual and flavor meridians,high-frequency clustering,related drug groups and complex network correlation,and summarize their medication laws and related treatment methods in the Essence of Huxiang Famous Physicians′ Books.Results A total of 67 prescriptions for the treatment of madness were included in the Essence of Huxiang Famous Physicians′ Books,with a total of 147 herbs.There were 33 drugs with a frequency of ≥5,which were used a total of 293 times,accounting for 59.19% of the frequency of use of all drugs.Their efficacy is mainly based on 11 types of medicines such as tonic,heat-clearing,phlegm-relieving,coughrelieving and asthma-relieving medicines.Their properties mainly involve cold,warm and mild drugs,and their tastes mainly involve bitter,sweet and pungent.Statistics on the frequency of meridians return of organs show that they mainly involve lung,spleen,heart,stomach,liver and kidney.Fifteen core drug pairs were obtained by drug association rule analysis,among which "Licorice-Angelica" drug pair had the highest support.Licorice,Poria cocos,Tangerine peel,Pinellia ternata and other drugs were mainly used for compatibility,which was consistent with the C7 clustering drugs in the high-frequency cluster analysis results.Nine new drug combinations were obtained by high-frequency cluster analysis.Conclusion Ancient doctors of Huxiang medical school had attached importance to treat madness mainly by resolving phlegm and purging fire,eliminating evil,and also focusing on strengthening the righteousness.In addition,they needed to treat the meridians separately,treat the five zang organs separately,or treat the five zang organs together,and pay attention to healing.
李树； 单焱亮. 古代湖湘医派医家辨治癫狂病处方用药规律分析[J]. 中国当代医药, 2022, 29(22): 156-160.
LI Shu1 SHAN Yanliang. Analysis of prescription medication law of ancient doctors of Huxiang medical school in the treatment of madness. 中国当代医药, 2022, 29(22): 156-160.
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