Abstract：Objective To investigate the application effect of traditional Chinese medicine combined with acupuncture on ovulation induction cycle in intrauterine insemination.Methods A total of 84 patients with intrauterine insemination(128 ovulation induction cycles in total) admitted to the Reproductive Center of Nanping People′s Hospital from January to December 2018 were selected as the research objects,and were divided into control group (42 cases,62 ovulation induction cycles) and observation group (42 cases,66 ovulation induction cycles) according to the random number table method.The control group was treated with Clomiphene Citrate/Letrozole/injection of Urinary Follicle-Stimulating Hormone + human chorionic gonadotropin (HCG) + intrauterine insemination.On the basis of treatment in the control group,the observation group was added with traditional Chinese medicine combined with acupuncture.The serum luteinizing hormone (LH) and estradiol (E2) values of the two groups were observed on HCG day,and the endometrial typing,endometrial thickness and pregnancy status of the two groups were compared..Results There were no significant differences in serum LH and E2 on HCG day between the two groups (P>0.05).The endometrial type in the observation group was better than that in the control group,and the endometrial thickness was higher than that in the control group,with statistically significant differences (P<0.05).The incidence of luteinized unruptured follicle syndrome in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).The incidence rates of intrauterine pregnancy,spontaneous abortion and ectopic pregnancy were compared between the two groups,and the differences were not statistically significant (P>0.05).Conclusion Traditional Chinese medicine combined with acupuncture therapy can improve the type and thickness of endometrium,reduce the incidence of luteinized unruptured follicle syndrome,which is worthy of promotion
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WANG Ying ；PAN Li-zhen； CHEN Xian. Application effect of traditional Chinese medicine combined with acupuncture on ovulation induction cycle in intrauterine insemination. 中国当代医药, 2020, 27(36): 159-162.
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