Abstract:Objective To investigate the effect and safety of Aspirin and Nimodipine in the treatment of migraine.Methods A total of 100 patients with migraine admitted to the hospital from January 2018 to June 2019 were selected as the research objects and divided into the control group and the observation group by random number table method,with 50 patients in each group.The control group was treated with Nimodipine,while the observation group was treated with Aspirin.The total effective rate,adverse reactions,migraine attacks and recurrence rates of the two groups were compared..Results The total effective rate of the observation group (92.00%) was higher that of the control group(72.00%),and the difference was statistically significant (P<0.05).The total incidence of adverse reactions in the observation group (8.00%) was lower than that in the control group (28.00%),and the difference was statistically significant(P<0.05).After treatment,the number of migraine attacks in the observation group was less than that in the control group,duration of migraine in the observation group was shorter than that in the control group,the visual analogue scale (VAS) score of the observation group was lower than that of the control group,and the differences were statistically significant (P<0.05).The recurrence rate of the observation group (4.00%) was lower than that of the control group(20.00%),and the difference was statistically significant (P<0.05).Conclusion For patients with migraine,Aspirin treatment is more effective than Nimodipine,which is suitable for clinical application and promotion.
孙辉;罗世书;王玉娟. 阿司匹林和尼莫地平治疗偏头痛的效果及安全性[J]. 中国当代医药, 2020, 27(36): 148-150.
SUN Hui;LUO Shi-shu;WANG Yu-juan. Effect and safety of Aspirin and Nimodipine in the treatment of migraine. 中国当代医药, 2020, 27(36): 148-150.