不同部位甲强龙局部注射治疗低频下降型突发性聋伴2型糖尿病的效果比较

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摘要目的对比研究耳后注射与鼓室内注射甲强龙治疗低频下降型突发性聋伴2型糖尿病的效果、并发症及对血糖的影响。方法选取2016年1月～2018年6月我院收治的72例伴2型糖尿病的低频下降型突发性聋患者，简单随机化法分为鼓室注射组与耳后注射组各36例。两组均行常规治疗，在此基础上，鼓室注射组、耳后注射组分别予以甲强龙行鼓室内、耳后注射。比较两组患者的临床疗效、不良反应。结果耳后注射组总有效率80.56%，鼓室注射组的总有效率66.67%，耳后注射组总有效率高于鼓室注射组，差异有统计学意义（P＜0.05）。治疗14 d后两组的听力阈值均低于治疗前，差异有统计学意义（P＜0.05）；耳后注射组的听力提高值高于鼓室注射组，差异有统计学意义（P＜0.05）。耳后注射组无鼓膜穿孔的风险，耳后注射组局部疼痛及一过性眩晕的发生率分别为22.22%、5.56%，鼓室注射组为63.89%、27.78%，鼓室注射组局部疼痛的比率及一过性眩晕的发生率均高于耳后注射组，差异有统计学意义（P＜0.05）。结论耳后注射甲强龙治疗伴2型糖尿病的低频下降型突发性聋患者效果较好，不良反应小，简单实用，可在临床中推广与应用。

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	刘丹
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关键词 ：甲强龙, 2型糖尿病, 突发性聋, 耳后注射

Abstract：Objective To compare the effect,complication and influgnce on blood glucose of tymamtic injection and retroaurel injection of Ankylosaurus in the treatment of low frequancy desconding suddon sensorineural hearing loss with type 2 diabetes..Methods From January 2016 to June 2018,72 patients with low-frequency descending sudden deafness accompanied by type 2 diabetes were selected and randomly divided into tympanic injection group and retroaural injection group with 36 cases each according to simple randomization.Both groups received conventional treatment.On this basis,the tympanic injection group and the posterior auricular injection group received methylprednisolone injections into the tympanic cavity and behind the ear,respectively.The clinical efficacy and adverse reactions of patients of the two groups were compared.Results The total effective rate of the post-auricular injection group was 80.56%,and the total effective rate of the tympanic injection group was 66.67%.The total effective rate of the post-auricular injection group was higher than that of the tympanic injection group,the difference was statistically significant(P＜0.05).After 14 days of treatment,the hearing thresholds of the two groups were lower than those before treatment,the differences were statistically significant (P＜0.05);the hearing improvement value of the behind the ear injection group was higher than that of the tympanic cavity injection group,the difference was statistically significant (P＜0.05).There was no risk of tympanic membrane perforation in the post-auricular injection group,the incidence of local pain and transient vertigo in the behind the ear injection group were 22.22% and 5.56%,respectively;the tympanic injection group was 63.89% and 27.78%,the rate of local pain and the incidence of transient vertigo in the tympanic cavity injection group were higher than those in the behind the ear injection group,the differences were statistically significant(P＜0.05).Conclusion Behind-auricular injection of methylprednisolone has good curative effect in the treatment of low-frequency descending sudden deafness with type 2 diabetes,and it is simple and practical.It can be popularized and applied in clinic.

Key words： Ankylosaurus Type 2 diabetes Sudden deafness Postaurical injection

引用本文:

刘丹;万浪; 彭聪;王桃娇. 不同部位甲强龙局部注射治疗低频下降型突发性聋伴2型糖尿病的效果比较[J]. 中国当代医药, 2020, 27(30): 117-120.
LIU Dan; WAN Lang; PENG Cong; WANG Tao-jiao. Effect comparison of local injection of Ankylosaurus in different parts for treating low frequency descending sudden sensorineural hearing loss in patients with type 2 diabetes. 中国当代医药, 2020, 27(30): 117-120.

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https://www.dangdaiyiyao.com/CN/ 或 https://www.dangdaiyiyao.com/CN/Y2020/V27/I30/117

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