难治性贫血和巨幼细胞性贫血骨髓形态学检验结果的比较

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摘要目的比较难治性贫血和巨幼细胞性贫血骨髓形态学的检验结果。结果选取2017年1月～2019年12月包头市肿瘤医院50例难治性贫血患者作为难治性贫血组，同期选取包头市肿瘤医院收治的50例巨幼细胞性贫血患者作为巨幼细胞性贫血组。两组患者均接受骨髓形态学检验，比较分析结果。结果难治性贫血组的有核红细胞过碘酸-碱性复红染色（PAS）阳性率高于巨幼细胞性贫血组，差异有统计学意义（P＜0.05）；难治性贫血组的淋巴样小巨核细胞阳性率、红系病变发生率高于巨幼细胞性贫血组，差异有统计学意义（P＜0.05）；难治性贫血组的粒系巨幼变发生率高于巨幼细胞性贫血组，差异有统计学意义（P＜0.05）；难治性贫血组的巨幼变原始红细胞体积、巨幼变早幼红细胞体积均小于巨幼细胞性贫血组，差异有统计学意义（P＜0.05）。结论在鉴别诊断难治性贫血和巨幼细胞性贫血过程中应用骨髓形态学检验，操作者应对巨核系病态造血加以强调，特别是淋巴样小巨核细胞现象；其次，针对巨幼细胞性贫血疾病特点，操作者应重点检测巨幼变幼红细胞体积，同时可以将有核红细胞PAS阳性率作为鉴别诊断难治性贫血及巨幼细胞性贫血的临床依据。

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	张莹

关键词 ：难治性贫血, 巨幼细胞性贫血, 骨髓形态学检验, 结果

Abstract：Objective To compare the results of bone marrow morphology of refractory anemia and megaloblastic anemia.Methods A total of 50 patients with refractory anemia in Baotou Tumor Hospital from January 2017 to December 2019 were selected as the refractory anemia group,and 50 patients with megaloblastic anemia Baotou Tumor Hospital were selected as the megaloblastic anemia group at the same time.Both groups received bone marrow morphology test and made a comparative analysis..Results The positive rate of periodate-alkaline red staining (PAS) of nucleated red blood cells in the refractory anemia group was higher than that in the megaloblastic anemia group,the differences were statistically significant (P<0.05); the rates of lymphoid small megakaryocytes and erythropathy in the refractory anemia group were higher than those in the megaloblastic anemia group,the differences were statistically significant (P<0.05);the incidence of granulomegaly in the refractory anemia group was higher than that in the megaloblastic anemia group,the differences were statistically significant (P<0.05); the volume of megaloblastic primordial erythrocytes and megaloblastic early erythrocytes in the refractory anemia group were smaller than those in the megaloblastic anemia group,the differences were statistically significant (P<0.05).Conclusion Application of bone marrow morphologic test in differential diagnosis of refractory anemia and megaloblastic anemia,especially the phenomenon of lymphoid small megakaryocyte.Secondly,according to the characteristics of megaloblastic anemia,the operator should focus on the detection of megaloblastic red blood cell volume,and at the same time,the positive rate of PAS of nucleated red blood cells can be used as the clinical basis for differential diagnosis of refractory anemia and megaloblastic anemia.

Key words： Refractory anemia Megaloblastic anemia Bone marrow morphology test Results

引用本文:

张莹. 难治性贫血和巨幼细胞性贫血骨髓形态学检验结果的比较[J]. 中国当代医药, 2020, 27(36): 74-76.
ZHANG Ying. Test result comparison of bone marrow morphology between refractory anemia and megaloblastic anemia. 中国当代医药, 2020, 27(36): 74-76.

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https://www.dangdaiyiyao.com/CN/ 或 https://www.dangdaiyiyao.com/CN/Y2020/V27/I36/74

[1]	喻甫国.难治性贫血与巨幼细胞性贫血的骨髓形态检验结果研究及意义[J].国际检验医学杂志，2018，39（13）：1662-1664.
[2]	徐军丽.巨幼细胞性贫血与难治性贫血骨髓形态检验对比分析[J].医学检验与临床，2019，30（1）：31-33.
[3]	黄秀群.骨髓细胞形态检验在难治性贫血与巨幼细胞性贫血鉴别中的临床价值[J].中外医疗，2019，38（6）：186-188.
[4]	张兰宁.骨髓形态学检验在鉴别诊断难治性贫血和巨幼细胞性贫血中的应用价值[J].当代医药论丛，2017，15（15）：152-153.
[5]	曾园红.骨髓细胞形态检验鉴别难治性贫血与巨幼细胞性贫血的临床价值[J].临床医药文献电子杂志，2017，4（89）：17 492-17 494.
[6]	张之南，沈悌.血液病诊断及疗效标准（第三版）[M].北京：科学出版社，2007.
[7]	苏静，裴兵，张建富.骨髓形态检验鉴别巨幼细胞性贫血与难治性贫血的临床价值[J].现代诊断与治疗，2017，28（5）：913-914.
[8]	曾艺.难治性贫血与巨幼细胞性贫血骨髓细胞形态学检验结果对比分析[J].中国急救医学，2018，38（Z2）：95.
[9]	刘洋，吴佳南.骨髓形态检验在难治性贫血与巨幼细胞性贫血鉴别诊断中的应用[J].中国民康医学，2018，30（22）：106-107.
[10]	高洋.骨髓形态检验在难治性贫血与巨幼细胞性贫血鉴别诊断中的应用[J].中国医药指南，2017，15（7）：30-31.
[11]	王志玲.巨幼细胞性贫血与难治性贫血的细胞形态学的鉴别[J].内蒙古医学杂志，2016，48（7）：799-801.
[12]	杨秀丽.骨髓形态学在难治性贫血、巨幼细胞贫血诊断中的意义[J].临床医药文献电子杂志，2018，5（22）：151.
[13]	张聪明，曾小敏.细胞形态学检查在鉴别诊断难治性贫血与巨幼细胞性贫血方面的临床价值[J].当代医药论丛，2016，14（3）：19-20.
[14]	张冬梅.难治性贫血与巨幼细胞性贫血的骨髓形态检验对比观察[J].中国社区医师，2017，33（28）：121-123.
[15]	王岩.贫血与巨幼细胞性贫血鉴别诊断中的临床价值[J].当代医学，2017，23（8）：112-113.