海带大蒜粥联合倍他乐克及通心络胶囊对冠心病心绞痛患者心电图及心功能指标的影响

摘要
图/表
参考文献(15)
相关文章 (15)

全文: PDF (0 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要目的探讨海带大蒜粥联合倍他乐克及通心络胶囊对冠心病心绞痛患者心电图、心功能指标及心绞痛症状的影响。方法选取2018年1月～2020年1月于江西省景德镇市第三人民医院太白园分院就诊的94例冠心病心绞痛患者作为研究对象，按照随机数字表法将其分为对照组与观察组，每组各47例。对照组患者予以倍他乐克联合通心络胶囊治疗，观察组患者在对照组的基础上加用海带大蒜粥治疗。比较两组患者的疗效、心功能指标、心绞痛发作次数及持续时间、不良反应总发生率。结果观察组患者的治疗总有效率为95.74%，高于对照组的82.98%，差异有统计学意义（P＜0.05）。治疗前，两组患者的心功能指标、心绞痛发作次数及持续时间比较，差异无统计学意义（P＞0.05）。治疗后，观察组患者的左室舒张末内径（LVEDD）为（42.39±5.72）mm，低于对照组的（49.82±5.94）mm；心排血量（CO）为（5.06±0.78）L/min，高于对照组的（4.53±0.71）L/min；左室射血分数（LVEF）为（55.39±5.61）%，高于对照组的（50.41±5.42）%，差异均有统计学意义（P＜0.05）。治疗后，观察组患者的心绞痛发作次数为（2.14±0.27）次/周，少于对照组的（2.61±0.36）次/周；持续时间为（3.18±0.35）min，短于对照组的（4.31±0.96）min，差异均有统计学意义（P＜0.05）。两组患者的不良反应总发生率比较，差异无统计学意义（P＞0.05）。结论海带大蒜粥联合倍他乐克及通心络胶囊可增强冠心病心绞痛患者的治疗效果，利于改善患者的心功能，减少心绞痛发作次数，缩短持续时间，安全可靠，值得广泛应用。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	沈勇

关键词 ：冠心病, 心绞痛, 海带大蒜粥, 倍他乐克, 通心络胶囊, 心功能, 不良反应

Abstract：Objective To investigate the effect of kelp garlic porridge combined with Betaloc and Tongxinluo Capsules on electrocardiogram (ECG),cardiac function indexes and angina symptoms in patients with angina pectoris and coronary heart disease.Methods A total of 94 patients with angina pectoris and coronary heart disease who admitted to Taibaiyuan Branch of the Third People′s Hospital of Jingdezhen City from January 2018 to January 2020 were selected as the research objects and divided into the control group and the observation group by random number table method,with 47 cases in each group.The control group was treated with Betaloc combined with Tongxinluo Capsules,and the observation group was treated with kelp garlic porridge on the basis of the control group.The therapeutic effect,cardiac function indexes,the frequency and duration of angina pectoris,the total incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group (95.74%) was higher than that of the control group (82.98%),and the difference was statistically significant (P＜0.05).There were no statistically significant differences in the cardiac function indexes,the frequency and duration of angina pectoris before treatment between the two groups (P＞0.05).After treatment,the left ventricular end-diastolic dimension (LVEDD) of the observation group([42.39±5.72]mm) was lower than that of the control group ([49.82±5.94]mm),the cardiac output (CO) of the observation group ([5.06±0.78]L/min) was higher than that of the control group ([4.53±0.71]L/min),the left ventricular ejection fraction (LVEF) of the observation group ([55.39±5.61]%) was higher than that of the control group ([50.41±5.42]%),and the differences were statistically significant (P＜0.05).After treatment,the frequency of angina pectoris in the observation group ([2.14±0.27]times per week) was less than that in the control group ([2.61±0.36]times per week),the duration of angina pectoris ([3.18±0.35]min) was less than that in the control group ([4.31±0.96]min),and the differences were statistically significant (P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion Kelp garlic porridge combined with Betaloc and Tongxinluo Capsules can enhance the therapeutic effect of patients with angina pectoris and coronary heart disease,improve the heart function of patients,reduce the frequency and duration of angina pectoris,which is safe and reliable,and it is worthy of wide application.

Key words： Coronary heart disease Angina pectoris Kelp garlic porridge Betaloc Tongxinluo Capsules Cardiac function Adverse reactions

作者简介: 沈勇（1979-），男，江西景德镇人，本科，主治医师，研究方向：中西医结合

引用本文:

沈勇. 海带大蒜粥联合倍他乐克及通心络胶囊对冠心病心绞痛患者心电图及心功能指标的影响[J]. 中国当代医药, 2020, 27(35): 75-78.
SHEN Yong. Effect of kelp garlic porridge combined with Betaloc and Tongxinluo Capsules on electrocardiogram and cardiac function indexes in patients with angina pectoris and coronary heart disease. 中国当代医药, 2020, 27(35): 75-78.

链接本文:

https://www.dangdaiyiyao.com/CN/ 或 https://www.dangdaiyiyao.com/CN/Y2020/V27/I35/75

[1]	胡克霞，王建华.复方丹参滴丸治疗冠心病心绞痛的疗效分析[J].辽宁中医杂志，2017，44（7）：1427-1429.
[2]	陈元椿.美托洛尔联合辛伐他汀对冠心病心绞痛的治疗效果及对心功能、内皮功能与血脂水平的影响[J].中西医结合心脑血管病杂志，2018，16（15）：2208-2211.
[3]	章陈晨，刘凌琳，宋双双，等.通心络治疗冠心病心绞痛对氧化应激及炎性因子的影响[J].心脑血管病防治，2019，19（4）：366-367，376.
[4]	王明磊，杨秀慧，张红雷.通心络胶囊对冠心病心绞痛随机、双盲、安慰剂平行对照、多中心临床试验[J].世界中医药，2019，14（11）：2973-2977.
[5]	沈庆法.冠心病心绞痛的中西医诊治[J].中国临床医生，2009，37（7）：64-67.
[6]	吴保军.阿托伐他汀联合单硝酸异山梨酯治疗冠心病心绞痛的临床研究[J].现代药物与临床，2017，32（3）：411-414.
[7]	杨红，杨波，熊秋霞.冠脉宁通方结合美托洛尔治疗冠心病心绞痛疗效及对冠脉斑块的影响[J].陕西中医，2017，38（8）：1006-1007.
[8]	张汉明.通脉养心丸联合美托洛尔治疗冠心病心绞痛的临床疗效[J].安徽医药，2017，10（14）：23-24.
[9]	张芙蓉，齐茗，王红娟.阿托伐他汀联合倍他乐克对冠心病合并短暂性脑缺血患者血清Hcyhs-CRP 及血脂水平的影响[J].河北医学，2018，24（3）：393-396.
[10]	毛亚妮，刘杲.通心络胶囊治疗心绞痛患者的临床观察[J].世界中西医结合杂志，2019，14（7）：970-973.
[11]	南明花，焦晓民，李爽，等.通心络胶囊治疗气虚络瘀型不稳定型心绞痛有效性和安全性分析[J].辽宁中医药大学学报，2018，20（6）：156-159.
[12]	贲峰.通心络联合曲美他嗪改善冠心病心绞痛患者心功能及病情效果研究[J].解放军预防医学杂志，2018，36（12）：1532-1534.
[13]	刘立军，朱君，鲍骏，等.通心络胶囊联合氨氯地平阿托伐他汀钙片治疗冠心病心绞痛的临床研究[J].中国医药导报，2019，16（32）：135-139.
[14]	常国栋，陈英伟，许学升，等.通心络胶囊治疗冠心病的疗效及机制研究[J].中国循证心血管医学杂志，2018，10（6）：729-732.
[15]	梁家宝，李浪，贺文慨.大蒜素对大鼠冠状动脉微栓塞后心肌凋亡的影响[J].实用医学杂志，2018，34（3）：371-375.