Application and comparison of various treatment methods in the treatment of moderate and severe chronic obstructive pulmonary disease with anxiety or depression
FENG Xuan1 LE Liang2 NI Hong-yan3
1.Department of Respiratory Medicine,Jingdezhen First People′s Hospital
2.Department of Pharmacy,Jingdezhen First People′s Hospital
3.Department of Endocrinology,Jingdezhen First People′s Hospital
Abstract：Objective To compare the application effect of various treatment methods in the treatment of moderate and severe chronic obstructive pulmonary disease with anxiety or depression.Methods From January 2017 to November 2019,150 patients with moderate or severe chronic obstructive pulmonary disease combined with anxiety or depression were selected from Jingdezhen First People′s Hospital.They were divided into three groups by random number table method,50 cases in each group.Group A was treated with primary disease drugs + psychological counseling,group B was treated with primary disease drugs + adjuvant therapy with psychotropic drugs,group C was treated with psychological counseling + primary disease drugs + adjuvant therapy with psychotropic drugs.The clinical effect,anxiety and depression degree,lung function before and 6 months after treatment were compared among the three groups.Results The total clinical effective rate of group C (98.00%) was higher than that of group A (78.00%) and group B and(82.00%),the difference was statistically significant (P＜0.05).There were no significant differences in Hamilton anxiety scale (HAMA) score and Hamilton depression scale (HAMD) score among the three groups before treatment (P＞0.05).The HAMA score and HAMD score of group C after treatment were (8.03±1.51) points and (9.17±2.03) points,respectively,which were lower than those of group A ([12.21±3.01],[13.06±3.16]points) and group B ([11.62±2.26],[11.21±2.54]points),with statistically significant differences (P＜0.05).There were no significant differences among the three groups in the forced expiratory volume at 1 second(FEV1),the ratio of FEV1 to the expected value (FEV1%),the ratio of FEV1 to the forced vital capacity (FEV1/FVC) (P＞0.05).After treatment,FEV1 in group C was (2.21±0.65) L,FEV1% was (53.74±7.93),and FEV1/FVC was (58.55±6.64)%,higher than those in group A ([1.78±0.38]L,[46.51±7.41],[55.79±6.59]%) and group B ([1.89±0.49]L,[48.26±7.62],[55.83±6.32]%),with statistically significant differences (P＜0.05).Conclusion Psychological counseling + primary disease drugs + adjuvant therapy with psychotropic drugs are effective in the treatment of moderate and severe chronic obstructive pulmonary disease with anxiety or depression,which can improve the degree of anxiety and depression and lung function,improve the treatment effect,and promote the recovery of patients′ disease.
冯旋；乐亮；倪虹艳. 多种治疗手段在中、重度慢性阻塞性肺疾病合并焦虑或忧郁治疗中的应用及对比[J]. 中国当代医药, 2020, 27(35): 44-47.
FENG Xuan；LE Liang；NI Hong-yan. Application and comparison of various treatment methods in the treatment of moderate and severe chronic obstructive pulmonary disease with anxiety or depression. 中国当代医药, 2020, 27(35): 44-47.
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