Effect of Carboprost Ambutritol combined with Misoprostol on clinical efficacy and oxidative stress indexes in patients with postpartum hemorrhage of placenta previa
YE Hongli CHENG Kang GAO Chang▲
Department of Obstetrics and Gynecology,Huanggang Maternal and Child Health Hospital
Abstract: Objective To investigate the effect of Carboprost Ambutritol combined with Misoprostol on clinical efficacy and oxidative stress indexes in patients with postpartum hemorrhage of placenta previa.Methods A total of 92 patients with postpartum hemorrhage from placenta previa who were admitted in Huanggang Maternal and Child Health Hospital from September 2019 to October 2020 were selected as the research objects.They were divided into the observation group and the control group according to the random number table method,each group with 46 cases.The observation group was treated with Carboprost Ambutritol combined with Misoprostol,and the control group was treated with Misoprostol.The related clinical indicators and oxidative stress indicators were compared between the two groups.Results The 24 h postpartum blood loss in the observation group was less than that in the control group,and the hemostasis time and hospitalization time were shorter than those in the control group,with statistically significant differences (P<0.05).After treatment,the levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the two groups were higher than those before treatment,and the levels of lipid peroxide (LPO) in the two groups were lower than those before treatment,the levels of SOD and GSH-Px in observation group after treatment were higher than those in the control group,and the level of LPO in observation group after treatment was lower than that in the control group,the differences were statistically significant (P<0.05).Conclusion Carboprost Ambutritol combined with Misoprostol for postpartum hemorrhage patients with placenta previa can improve relevant clinical indicators and significantly regulate the level of oxidative stress indicators.
叶红丽;程康;高畅. 卡前列素氨丁三醇联合米索前列醇对前置胎盘产后出血患者临床疗效及氧化应激指标的影响[J]. 中国当代医药, 2022, 29(17): 123-125转129.
YE Hongli ;CHENG Kang ;GAO Chang. Effect of Carboprost Ambutritol combined with Misoprostol on clinical efficacy and oxidative stress indexes in patients with postpartum hemorrhage of placenta previa. 中国当代医药, 2022, 29(17): 123-125转129.