Abstract:Objective To explore the application effect of peripherally inserted central catheter (PICC) catheterization under electrocardiogram positioning in premature infant wards. Methods A total of 60 premature infants admitted to Department of Neonatology of Yingtan People′s Hospital were enrolled as research objects from May 2020 to January 2022, according to random number table method, they were divided into the observation group (30 cases) and the control group (30 cases). The control group was given intravenous indwelling needles catheterization, while observation group was given PICC catheterization under electrocardiogram positioning. The success rate of catheterization, catheterization time, hospitalization time, increment of body weight and the occurrence of complications in the two groups were compared. Results The success rate of one-time puncture in the observation group was higher than that in the control group, the difference was statistically significant (P<0.05). There was no significant difference in the success rate of the twice puncture between the two groups (P>0.05). The retention time of once catheterization in the observation group was longer than that in the control group, the total catheterization time and the total hospitalization time in the observation group were shorter than those in the control group, the differences were statistically significant (P<0.05). The increment of body weight in the observation group was greater than that in the control group, the difference was statistically significant (P<0.05). The incidence of complications after catheterization in the observation group was lower than that in the control group, the difference was statistically significant (P<0.05). Conclusion Compared with traditional intravenous catheterization, PICC catheterization under electrocardiogram positioning can effectively increase the success rate of catheterization, ensure intravenous nutrition supply and accelerate rehabilitation process. One-time catheterization can be retained for a long time, which can reduce the damage induced by multiple catheterization and effectively reduce the risk of related complications.