Clinical effect of Yiqi Huoxue Prescription add and subtract combined rehabilitation treatment in convalescent patients of ischemic stroke
WU Jinjuan1 MAO Ting2 HUANG Miao1 BAI Lijun1
1. Department of Integrated Traditional Chinese and Western Medicine, Shahe Hospital in Changping District, Beijing 102206, China;
2. Department of Cardiovascular, Changping District Hospital of Integrated Traditional Chinese and Western Medicine, Beijing 102206, China
Abstract：Objective To explore the effect of Yiqi Huoxue Prescription add and subtract combined rehabilitation treatment on the efficacy in convalescent patients of ischemic stroke (IS). Methods From June 2019 to June 2020, a total of 86 IS convalescent patients admitted to Shahe Hospital of Changping District in Beijing City were selected as study subjects. They were divided into study group and control group by drawing lots method, with 43 cases in each group. The control group was received with routine rehabilitation treatment for IS. The study group was treated with Yiqi Huoxue Prescription add and subtract combined rehabilitation treatment. Before and after treatment, the serum hypersensitivity C-reactive protein (hs-CRP), brain-derived neurotrophic factor (BDNF), the National Institutes of Health stroke scale (NIHSS) score, Barthel index rating scale score, and Fugel-Meyer assessmen (FMA) rating scale score were compared between the two groups. Results There were no statistical differences in hs-CRP and BDNF between the two groups (P>0.05). After treatment, the hs-CRP levels in both groups were lower than those before treatment, while BDNF levels in both groups were higher than those before treatment, with statistically significant differences (P<0.05). The hs-CRP of the study group was lower than that in control group, and BDNF was higher than that in control group, with statistically significant differences (P<0.05). There were no statistical differences in the NIHSS score, the Barthel index, as well as the FMA score between the two groups (P>0.05). After treatment, the NIHSS scores in both groups were lower than those before treatment, while the Barthel index and the FMA score in both groups were higher than those before treatment, with statistically significant differences (P<0.05). The NIHSS score of the study group was lower than that in control group, and Barthel index and the FMA score were higher than those in control group, with statistically significant differences (P<0.05). Conclusion For patients with IS recovery, Yiqi Huoxue Prescription add and subtract combined rehabilitation treatment can improve the inflammatory status, contribute to the generation of nutritional nerve-related factors, promote the recovery of neurological defects, so as to improve their limb function and self-care ability.
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