Abstract：Objective To explore the expression and clinical significance of resistin, copeptin and oxidized low-density lipoprotein in patients with acute ischemic stroke. Methods A total of 85 patients with acute ischemic stroke who were admitted to Changshu Second People′s Hospital affiliated to Yangzhou University from June to December 2019 were selected as the acute ischemic stroke group. Eighty-five healthy people who underwent physical examination in Changshu Second People′s Hospital at the same time were selected as healthy control group. The acute ischemic stroke group collected venous blood within 24 hours of onset to detect serum resistin, copeptin, ox-LDL levels, and compared the serum resistin, copeptin, ox-LDL level, draw ROC curve to analyze the predictive value of resistin, copeptin, ox-LDL and the combined detection of the three indicators in acute ischemic stroke. Results The levels of resistin, copeptin and ox-LDL in acute ischemic stroke group were higher than those in healthy control group, the differences were statistically significant (P<0.05). The levels of resistin, copeptin and ox-LDL in patients with moderate and large area cerebral infarction were higher than those in patients with lacunar cerebral infarction, and the differences were statistically significant (P<0.05). The levels of resistin, copeptin and ox-LDL in patients with large cerebral infarction were higher than those in patients with moderate cerebral infarction, and the differences were statistically significant (P<0.05). The levels of resistin, copeptin and ox-LDL in patients with moderate and severe neurological impairment were higher than those in patients with mild neurological im
基金资助:江苏省常熟市卫生健康委员会科技计划项目（cswsq201902）。
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▲通讯作者
作者简介: 高善玉（1987-），女，江苏苏州人，硕士，研究方向：脑血管病。
引用本文:
高善玉； 尤年兴. 抵抗素、和肽素、氧化型低密度脂蛋白在急性缺血性脑卒中患者中的表达及临床意义[J]. 中国当代医药, 2022, 29(19): 85-89.
GAO Shanyu； YOU Nianxing▲. Expression and clinical significance of resistin, copeptin and oxidized low density lipoprotein in patients with acute ischemic stroke. 中国当代医药, 2022, 29(19): 85-89.
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