Diagnostic value of CT perfusion imaging combined with mean arterial pressure in patients with severe craniocerebral trauma and its relationship with prognosis
LI Shiqing SONG Zengliang
Department of Neurosurgery, the Third Hospital of Nanchang, Jiangxi Province, Nanchang 330000, China
Abstract:Objective To investigate the diagnostic value of CT perfusion imaging (CTP) combined with mean arterial pressure (MAP) in patients with severe craniocerebral trauma and its relationship with prognosis. Methods A total of 90 patients with severe suspected craniocerebral trauma who were admitted to the Department of Neurosurgery of the Third Hospital of Nanchang from April 2019 to February 2021 were selected as the research objects. All patients underwent routine head CTP examination after admission, and the final clinical examination results were used as "golden standard". The diagnostic value was analyzed and the MAP level was monitored. The patients were followed up for 6 months, and the Glasgow coma index score (GOS) was used as the prognostic scoring standard. The patients were evaluated at 1, 6 months after treatment, and the correlation analysis was completed. Results Among 90 patients with severe suspected craniocerebral trauma, 62 patients were finally diagnosed by clinical examination, with a diagnosis rate of 68.89%. 57 patients were finally diagnosed by head CTP examination, and the coincidence rate with the "gold standard" diagnosis was 85.56% [(53+24)/90]. The diagnostic sensitivity was 85.48% (53/62), the specificity was 85.71% (24/28). The levels of cerebral blood perfusion rate (CBF), cerebral blood volume (CBV) and MAP in severe craniocerebral trauma were lower than those in non-severe craniocerebral trauma, and the differences were statistically significant (P<0.05). The mean transit time (MTT) and the time to peak contrast (TTP) were longer than those of non-severe craniocerebral trauma, and the differences were statistically significant (P<0.05). The average GOS score of patients with severe craniocerebral trauma was (3.13±0.63). The results of correlation analysis showed that the GOS score of patients with severe craniocerebral trauma was negatively correlated with the levels of CBF, CBV and MAP, and positively correlated with MTT and TTP (P<0.05). Conclusion CTP has high diagnostic value in patients with severe craniocerebral trauma. Combined examination with MAP can guide clinical treatment and has a strong correlation with the prognosis of patients.
李世清;宋增亮. CT脑灌注成像联合平均动脉压在重症颅脑外伤患者中的诊断价值及与预后的关系[J]. 中国当代医药, 2022, 29(19): 14-17.
LI Shiqing; SONG Zengliang. Diagnostic value of CT perfusion imaging combined with mean arterial pressure in patients with severe craniocerebral trauma and its relationship with prognosis. 中国当代医药, 2022, 29(19): 14-17.
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