Application effect of combined inhalation anesthesia induction device in reduction of developmental dysplasia of the hip in children
LI Kaihui LIU Shanshan▲ CAI Tieliang LI Xiaowei#br#
Department of Anesthesiology, People's Liberation Army Ground Force Seventy-three Military Hospital, Chenggong Hospital Affiliated to Xiamen University, Fujian Province, Xiamen 361000, China
Objective To observe the application effect of Sevoflurane inhalation by combined inhalation anesthesia induction device in reduction developmental dysplasia of the hip (DDH) in children. Methods A total of 97 children with the diagnosis of DDH were selected from the People's Liberation Army Ground Force Seventy-three Military Hospital,Chenggong Hospital affiliated to Xiamen University from January 2016 to January 2020, and divided into group G (n=49)and group D (n=48)by random number table method.The group G was inhaled Sevoflurane 2 ml once by using combined inhalation anesthesia induction device before manual reduction with the supplementary dose of Sevoflurane 2 ml once, and group D was injected Ketamine 4-5 mg/kg through deltoid muscle with the supplementary dose of 0.5 mg/kg intravenously. The mean arterial pressure (MAP), heart rate (HR), blood oxygen saturation (SpO2), sleeping latency, wakening time, and the total incidence of adverse events were collected and analyzed at pre-anesthesia (T1), pre-operation(T2), and post-operation (T3). Results There were no significant differences in MAP, HR and SpO2 between the two groups at T1 (P＞0.05). The fluctuation of MAP, HR in group G at T2 and T3 were lower than those in group D, with statistically differences (P＜0.05). There were no significant differences in SpO2 at T2 and T3 between group G and group D(P＞0.05). The fluctuation of MAP, HR in group Gg at T2 and T3 were lower than those in group Dd in children of who required manual reduction after adductor amputation,with statistically differences (P<0.05).There were no significant differences in SpO2 at T2 and T3 between group Gg and group Dd (P＞0.05). The sleep latency in group G was longer than that in group D,with statistically difference(P<0.05).The awakening time was shorter than that in group D, with statistically difference (P<0.05). The total incidence of adverse events in group G was lower than that in group D, with statistically difference (P<0.05). Conclusion Compared with traditional anesthesia applied by ketamine, the inhalation of Sevoflurane by combined inhalation anesthesia induction device during manual reduction of DDH in children were more humanization and safety, and with the advantages of stable anesthesia, rapid recovery and less incidence of adverse events. It is a safe and effective anesthesia method.
李凯辉；刘珊珊； 蔡铁良；黎笑微. 组合式吸入麻醉诱导装置在小儿发育性髋关节脱位复位手术中的应用效果[J]. 中国当代医药, 2022, 29(18): 107-110.
LI Kaihui LIU Shanshan▲ CAI Tieliang LI Xiaowei. Application effect of combined inhalation anesthesia induction device in reduction of developmental dysplasia of the hip in children. 中国当代医药, 2022, 29(18): 107-110.
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，补充剂量为氯胺酮0.5 mg/（kg·次）静脉滴注。分析与统计两组患儿麻醉前（T1）、手术开始前（T2）、术毕清醒时（T3）的平均动脉压（MAP）、心率（HR）、血氧饱和度（SpO2），入睡时间、清醒时间及术中不良反应总发生率。 结果 两组患儿T1 时MAP、HR、SpO2 比较，差异无统计学意义（P＞0.05）。G 组患儿T2、T3 时MAP、HR、低于D 组，差异有统计学意义（P＜0.05），两组T2、T3 的SpO2 比较，差异无统计学意义（P＞0.05）；在需要内收肌切断后手法复位的患儿中，Gg 组T2、T3 时MAP、HR 低于Dd 组，差异有统计学意义（P<0.05），两组T2、T3 的SpO2 比较，差异无统计学意义（P＞0.05）。G 组患儿入睡时间长于D 组，差异有统计学意义（P<0.05），清醒时间短于D 组，差异有统计学意义（P<0.05）。G 组患儿术中不良反应总发生率低于D 组，差异有统计学意义（P<0.05）。结论 小儿发育性髋关节脱位手法复位时与传统氯胺酮麻醉比较，采用组合式吸入麻醉诱导装置吸入七氟醚麻醉具有更人性化、更安全，以及诱导舒适、苏醒迅速、不良反应少等优点，是一种安全有效的麻醉方法。
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